"Some embodiments of the invention relate to minimal motifs of linear B-cell epitopes in L1 protein from HPV 58. These motifs have the amino acid sequences listed below: SEQ ID No. 1: YLPPVP, labeled as HPV58/L1-1.sup.38-43; or SEQ ID No. 2: PNKFGP, labeled as HPV58/L1-2.sup.107-112; or SEQ ID No. 2B: GHPYLN, labeled as HPV58/L1-2B.sup.146-151; or SEQ ID No. 3: DDTE, labeled as HPV58/L1-3.sup.154-157; or SEQ ID No. 3B: YPAQPGS, labeled as HPV58/L1-3B.sup.162-168; or SEQ ID No. 4: ATDC, labeled as HPV58/L1-4.sup.208-211; or SEQ ID No. 5: PLELF, labeled as HPV58/L1-5.sup.213-217; or SEQ ID No. 6: EDGDMV, labeled as HPV58/L1-6.sup.222-227; or SEQ ID No. 7: DTGF, labeled as HPV58/L1-7.sup.228-231; or SEQ ID No. 8: FGTLQAN, labeled as HPV58/L1-8.sup.236-242; or SEQ ID No. 9: DVPID, labeled as HPV58/L1-9.sup.245-249; or SEQ ID No. 10: PDDL, labeled as HPV58/L1-10.sup.298-301; or SEQ ID No. 11: QLFNK, labeled as HPV58/L1-11.sup.331-335; or SEQ ID No. 12: GTYK, labeled as HPV58/L1-12.sup.378-381; or SEQ ID No. 13: DNFKEY, labeled as HPV58/L1-13.sup.383-388; or SEQ ID No. 14: KEDP, labeled as HPV58/L1-14.sup.462-465; or SEQ ID No. 15: KAKPRLK, labeled as HPV58/L1-15.sup.500-506; or SEQ ID No. 16: SAP, labeled as HPV58/L1-16.sup.508-510.
"Some embodiments of the invention relate to peptides (e.g., 8-mer peptides) containing the minimal motifs described above. For example, such peptides may comprise any of the amino acid sequences listed below: SEQ ID No. 17: X.sub.1YLPPVPX.sub.2 (labeled as L1-1; both X.sub.1 and X.sub.2 represent V); or SEQ ID No. 18: X.sub.1PNKFGPX.sub.2 (labeled as L1-2; X.sub.1 represents D while X.sub.2 represents P); or SEQ ID No. 18B: X.sub.1GHPYLNX.sub.2 (labeled as L1-2B; X.sub.1 represents S while X.sub.2 represents K); or SEQ ID No. 19: X.sub.1X.sub.2DDTEX.sub.3X.sub.4 (labeled as L1-3; X.sub.1 represents K and X.sub.2 represents F while X.sub.3 represents T and X.sub.4 represents S); or SEQ ID No. 19B: X.sub.1 YPAQPGS (labeled as L1-3B; X.sub.1 represents R); or SEQ ID No. 20: X.sub.1X.sub.2ATDCX.sub.3X.sub.4(labeled as L1-4; both X.sub.1 and X.sub.2 represent A while both X.sub.3 and X.sub.4 represent P); or SEQ ID No. 21: X.sub.1PLELFX.sub.2X.sub.3(labeled as L1-5; X.sub.1 represents P and X.sub.2 represents N while X.sub.3 represents S); or SEQ ID No. 22: X.sub.1EDGDMVX.sub.2 (labeled as L1-6; X.sub.1 represents I while X.sub.2 represents D); or SEQ ID No. 23: X.sub.1X.sub.2DTGFX.sub.3X.sub.4 (labeled as L1-7; X.sub.1 represents M and X.sub.2 represents V while X.sub.3 represents G and X.sub.4 represents C); or SEQ ID No. 24: X.sub.1FGTLQAN (labeled as L1-8; X.sub.1 represents D); or SEQ ID No. 25: X.sub.1X.sub.2DVPIDX.sub.3(labeled as L1-9; X.sub.1 represents K and X.sub.2 represents S while X.sub.3 represents I); or SEQ ID No. 26: X.sub.1X.sub.2PDDLX.sub.3X.sub.4 (labeled as L1-10; X.sub.1 represents A and X.sub.2 represents V while X.sub.3 represents Y and X.sub.4 represents I); or SEQ ID No. 27: X.sub.1X.sub.2QLFNKX.sub.3 (labeled as L1-11; X.sub.1 represents E and X.sub.2 represents S while X.sub.3 represents P); or SEQ ID No. 28: X.sub.1X.sub.2GTYKX.sub.3X.sub.4 (labeled as L1-12; X.sub.1 represents K and X.sub.2 represents E while X.sub.3 represents N and X.sub.4 represents D); or SEQ ID No. 29: X.sub.1DNFKEYX.sub.2 (labeled as L1-13; X.sub.1 represents N while X.sub.2 represents V); or SEQ ID No. 30: X.sub.1X.sub.2KEDPX.sub.3X.sub.4 (labeled as L1-14; X.sub.1 represents K and X.sub.2 represents E while X.sub.3 represents L and X.sub.4 represents N); or SEQ ID No. 31: X.sub.1KAKPRLK (labeled as L1-15; X.sub.1 represents L); or SEQ ID No. 32: X.sub.1X.sub.2X.sub.3SAPX.sub.4X.sub.5(labeled as L1-16; X.sub.1 represents L; X.sub.2 represents K and X.sub.3 represents R while both X.sub.4 and X.sub.5 represents T), wherein X.sub.1, X.sub.2, X.sub.3, X.sub.4, and X.sub.6 each represent a specific amino acid residue noted above.
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