News Column

Study Findings from Stanford University Broaden Understanding of Peptides and Proteins (Simultaneous Purification and Fractionation of Nucleic Acids...

September 9, 2014



Study Findings from Stanford University Broaden Understanding of Peptides and Proteins (Simultaneous Purification and Fractionation of Nucleic Acids and Proteins from Complex Samples Using Bidirectional Isotachophoresis)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Peptides and Proteins. According to news originating from Stanford, California, by NewsRx correspondents, research stated, "We report on our efforts to create an on-chip system to simultaneously purify and fractionate nucleic acids and proteins from complex samples using isotachophoresis (ITP). We have developed this technique to simultaneously extract extracellular DNA and proteins from human blood serum samples and deliver these to two separate output reservoirs on a chip."

Our news journalists obtained a quote from the research from Stanford University, "The purified DNA is compatible with quantitative polymerase chain reaction (qPCR), and proteins can be extracted so as to exclude albumin, the most abundant protein in serum. We describe significant remaining challenges in making this bidirectional method a robust and efficient technique."

According to the news editors, the research concluded: "These challenges include managing channel surface adsorption of proteins, identifying the cause of observed reductions in low molecular weight proteins, and dealing with nonspecific binding of proteins and DNA."

For more information on this research see: Simultaneous Purification and Fractionation of Nucleic Acids and Proteins from Complex Samples Using Bidirectional Isotachophoresis. Analytical Chemistry, 2014;86(15):7264-7268. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)

The news correspondents report that additional information may be obtained from Y.T. Qu, Stanford University, Dept. of Chem Engn, Stanford, CA 94305, United States. Additional authors for this research include L.A. Marshall and J.G. Santiago (see also Peptides and Proteins).

Keywords for this news article include: Stanford, California, United States, North and Central America, Amino Acids, Peptides, Peptides and Proteins, Proteins

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


For more stories covering the world of technology, please see HispanicBusiness' Tech Channel



Source: Life Science Weekly


Story Tools






HispanicBusiness.com Facebook Linkedin Twitter RSS Feed Email Alerts & Newsletters