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Studies from Xuzhou Medical College Reveal New Findings on Sulfur Amino Acids (Colorimetric sensing of cysteine using label-free silver nanoparticles)

September 9, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Sulfur Amino Acids are discussed in a new report. According to news reporting originating from Xuzhou, People's Republic of China, by NewsRx correspondents, research stated, "The development of methods for the effective measurement of cysteine in biological fluids is of great physiological and pathological importance. In this study, we present a convenient and economical colorimetric method for the quantitative determination of cysteine using label-free silver nanoparticles (Ag NPs) as color indicators and Ca2+ ions as cross-linking agents."

Our news editors obtained a quote from the research from Xuzhou Medical College, "The simultaneous addition of cysteine and Ca2+ to a Ag NPs colloidal solution results in the cross-linking of the Ag NPs, leading to a rapid yellow-to-red color change. In this way, a simple and rapid method for the quantitative assay of cysteine in the linear range of 0.1-1000 mu M was obtained through monitoring of absorbance signatures. This convenient technique exhibited high selectivity toward cysteine over a range of other amino acids, as well some thiol-containing compounds."

According to the news editors, the research concluded: "Importantly, our newly developed method was successfully applied to the detection of cysteine in biological fluids, such as serum and artificial cerebrospinal fluid based on changes in the color of these solutions in less than 10 min."

For more information on this research see: Colorimetric sensing of cysteine using label-free silver nanoparticles. Sensors and Actuators B-Chemical, 2014;202():574-582. Sensors and Actuators B-Chemical can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also Sulfur Amino Acids).

The news editors report that additional information may be obtained by contacting C.P. Han, Xuzhou Medical College, Affiliated Hosp, Dept. of Radiol, Xuzhou 221004, People's Republic of China. Additional authors for this research include K. Xu, Q. Liu, X.H. Liu and J.J. Li.

Keywords for this news article include: Xuzhou, People's Republic of China, Asia, Cysteine, Emerging Technologies, Nanoparticle, Nanotechnology, Neutral Amino Acids, Sulfhydryl Compounds, Sulfur Amino Acids

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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