Researchers from University of Belgrade Report Findings in Nanoparticles (A comprehensive approach to in vitro functional evaluation of Ag/alginate nanocomposite hydrogels)
By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Nanoparticles is the subject of a report. According to news originating from Belgrade, Serbia, by NewsRx correspondents, research stated, "In this work, we present a comprehensive approach to evaluation of alginate microbeads with included silver nanoparticles (AgNPs) at the concentration range of 0.3-5 mM for potential biomedical use by combining cytotoxicity, antibacterial activity, and silver release studies. The microbeads were investigated regarding drying and rehydration showing retention of similar to 80-85% of the initial nanoparticles as determined by UV-vis and SEM analyses."
Our news journalists obtained a quote from the research from the University of Belgrade, "Both wet and dry microbeads were shown to release AgNPs and/or ions inducing similar growth delays of Staphylococcus aureus and Escherichia coli at the total released silver concentrations of similar to 10 mu g/ml. On the other hand, these concentrations were highly toxic for bovine chondrocytes in conventional monolayer cultures while nontoxic when cultured in alginate microbeads under biomimetic conditions in 3D perfusion bioreactors."
According to the news editors, the research concluded: "The applied approach outlined directions for further optimization studies demonstrating Ag/alginate microbeads as potentially attractive components of soft tissue implants as well as antimicrobial wound dressings."
For more information on this research see: A comprehensive approach to in vitro functional evaluation of Ag/alginate nanocomposite hydrogels. Carbohydrate Polymers, 2014;111():305-314. Carbohydrate Polymers can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Carbohydrate Polymers - www.elsevier.com/wps/product/cws_home/405871)
The news correspondents report that additional information may be obtained from J. Stojkovska, University of Belgrade, Fac Technol & Met, Belgrade 11000, Serbia. Additional authors for this research include D. Kostic, Z. Jovanovic, M. Vukasinovic-Sekulic, V. Miskovic-Stankovic and B. Obradovic (see also Nanoparticles).
Keywords for this news article include: Belgrade, Serbia, Europe, Emerging Technologies, Nanoparticle, Nanoparticles, Nanotechnology
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