Researchers from Istanbul Technical University Report Details of New Studies and Findings in the Area of Antibiotics (Electrospun antibacterial nanofibrous polyvinylpyrrolidone/cetyltrimethylammonium bromide membranes for biomedical applications)
By a News Reporter-Staff News Editor at Anti-Infectives Week -- Current study results on Drugs and Therapies have been published. According to news reporting originating in Istanbul, Turkey, by NewsRx journalists, research stated, "Nanoscale structures with large surface area-to-volume ratios are used as biomaterial scaffolds for vascular grafts, wound dressings, and air purifying filters. Using electrospinning, nanofibers containing an antibacterial agent, cetyltrimethylammonium bromide, were prepared for wound healing application."
The news reporters obtained a quote from the research from Istanbul Technical University, "Polyvinylpyrrolidone, known as a biocompatible additive in food and drug industries, has been used as fiber processing agent with the organic active ingredient, cetyltrimethylammonium bromide. A series of samples with different polyvinylpyrrolidone/ cetyltrimethylammonium bromide ratios were successfully prepared by this method. The morphology and electroactive characteristics of nanofibers were investigated using scanning electron microscopy, atomic force microscopy, and electrochemical impedance spectroscopy. Fiber diameters and charge transfer resistances were found to decrease with salt content, while the double-layer capacitance increased with no apparent effect on the specific capacitance providing favorable conditions for the fabrication of biomaterials."
According to the news reporters, the research concluded: "In addition, the quaternary ammonium compound (cetyltrimethylammonium bromide) with a minimum ratio of 2.5 wt% showed reduction in bacterial activity of Klebsiella pneumonia, Staphylococcus aureus, and Escherichia coli."
For more information on this research see: Electrospun antibacterial nanofibrous polyvinylpyrrolidone/cetyltrimethylammonium bromide membranes for biomedical applications. Journal of Bioactive and Compatible Polymers, 2014;29(4):382-397. Journal of Bioactive and Compatible Polymers can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Journal of Bioactive and Compatible Polymers - jbc.sagepub.com)
Our news correspondents report that additional information may be obtained by contacting N. Uykun, Istanbul Technical University, Fac Text Technol & Design, TR-34469 Istanbul, Turkey. Additional authors for this research include I. Ergal, H. Kurt, A.T. Gokceoren, I. Gocek, B.K. Kayaoglu, A.T. Akarsubasi and A.S. Sarac (see also Drugs and Therapies).
Keywords for this news article include: Istanbul, Turkey, Eurasia, Antibacterial, Antibiotics, Antimicrobials, Drugs and Therapies, Emerging Technologies, Hydrocarbons, Nanofiber, Nanotechnology, Organic Chemicals, Polyenes, Polyvinyls, Therapy, Vinyl Compounds
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