Report Summarizes Nanoparticles Study Findings from Department of Chemistry (Magnetic control of protein spatial patterning to direct microtubule self-assembly)
By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Nanoparticles is now available. According to news reporting out of Paris, France, by NewsRx editors, research stated, "Living systems offer attractive strategies to generate nanoscale structures because of their innate functional properties such as the dynamic assembly of ordered nanometer fibers, the generation of mechanical forces, or the directional transport mediated by molecular motors. The design of hybrid systems, capable of interfacing artificial building blocks with biomolecules, may be a key step toward the rational design of nanoscale devices and materials."
Our news journalists obtained a quote from the research from the Department of Chemistry, "Here, we have designed a bottom-up approach to organize cytoskeletal elements in space using the self-assembly properties of magnetic nanoparticles conjugated to signaling proteins involved in microtubule nucleation. We show that magnetic nanoparticles conjugated to signaling proteins involved in microtubule nucleation can control the positioning of microtubule assembly. Under a magnetic field, a self-organized pattern of biofunctionalized nanoparticles is formed and leads to the nucleation of a periodical network of microtubules in Xenopus laevis egg extract."
According to the news editors, the research concluded: "Our method shows how bioactive nanoparticles can generate a biochemically active pattern upon magnetic actuation, which triggers the spatial organization of nonequilibrium biological structures."
For more information on this research see: Magnetic control of protein spatial patterning to direct microtubule self-assembly. Acs Nano, 2013;7(11):9647-54. (American Chemical Society - www.acs.org; Acs Nano - www.pubs.acs.org/journal/ancac3)
Our news journalists report that additional information may be obtained by contacting C. Hoffmann, Dept. of Chemistry, Ecole Normale Superieure , UMR 8640 CNRS-ENS-UPMC Pasteur, 24 rue Lhomond, 75005 Paris, France. Additional authors for this research include E. Mazari, C. Gosse, L. Bonnemay, S. Hostachy, J. Gautier and Z. Gueroui (see also Nanoparticles).
Keywords for this news article include: Paris, France, Europe, Emerging Technologies, Nanoparticle, Nanoparticles, Nanoscale, Nanotechnology.
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