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New Nanoparticles Study Results from North Dakota State University Described (Novel starch based nano scale enteric coatings from soybean meal for...

September 9, 2014



New Nanoparticles Study Results from North Dakota State University Described (Novel starch based nano scale enteric coatings from soybean meal for colon-specific delivery)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators discuss new findings in Nanoparticles. According to news reporting from Fargo, North Dakota, by NewsRx journalists, research stated, "Soybean meal was used to isolate resistant starch and produce nanoparticles, which could be potential coating materials for colonic nutrient and drug deliveries. The nanoparticles were in 40 +/- 33.2 nm ranges."

The news correspondents obtained a quote from the research from North Dakota State University, "These nanoparticles were stable under simulated human physiological conditions. The degrees of dissolution in both stomach and intestinal conditions were less than 30%. Furthermore, the nanoparticles were less susceptible to pancreatic enzymatic digestion (20%), which was also evidenced by the co-existence of B-type crystalline pattern. In addition to the dissolution and digestion studies in the upper gastrointestinal tract, the nanoparticles were subjected to in vitro fermentation by Bifidobacterium brevis and Lactobacillus casei. Both species showed an increase in growth and activity, while producing short chain fatty acids: acetate, propionate, and butyrates in varying amounts."

According to the news reporters, the research concluded: "Overall this study clearly demonstrated a novel method that can be used for colon-specific delivery of bioactive compounds such as drugs and nutrients."

For more information on this research see: Novel starch based nano scale enteric coatings from soybean meal for colon-specific delivery. Carbohydrate Polymers, 2014;111():273-279. Carbohydrate Polymers can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Carbohydrate Polymers - www.elsevier.com/wps/product/cws_home/405871)

Our news journalists report that additional information may be obtained by contacting N. Sivapragasam, North Dakota State University, Fargo, ND 58108, United States. Additional authors for this research include P. Thavarajah, J.B. Ohm, J.B. Ohm, K. Margaret and D. Thavarajah (see also Nanoparticles).

Keywords for this news article include: Fargo, North Dakota, United States, North and Central America, Emerging Technologies, Nanoparticle, Nanoparticles, Nanotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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