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New Molecular Biology Study Findings Have Been Reported from Shanghai Ocean University (MicroRNA repertoire for functional genome research in tilapia...

September 10, 2014



New Molecular Biology Study Findings Have Been Reported from Shanghai Ocean University (MicroRNA repertoire for functional genome research in tilapia identified by deep sequencing)

By a News Reporter-Staff News Editor at Biotech Week -- Fresh data on Life Science Research are presented in a new report. According to news reporting originating in Shanghai, People's Republic of China, by NewsRx journalists, research stated, "The Nile tilapia (Oreochromis niloticus; Cichlidae) is an economically important species in aquaculture and occupies a prominent position in the aquaculture industry. MicroRNAs (miRNAs) are a class of noncoding RNAs that post-transcriptionally regulate gene expression involved in diverse biological and metabolic processes."

The news reporters obtained a quote from the research from Shanghai Ocean University, "To increase the repertoire of miRNAs characterized in tilapia, we used the Illumina/Solexa sequencing technology to sequence a small RNA library using pooled RNA sample isolated from the different developmental stages of tilapia. Bioinformatic analyses suggest that 197 conserved and 27 novel miRNAs are expressed in tilapia. Sequence alignments indicate that all tested miRNAs and miRNAs* are highly conserved across many species. In addition, we characterized the tissue expression patterns of five miRNAs using real-time quantitative PCR. We found that miR-1/206, miR-7/9, and miR-122 is abundantly expressed in muscle, brain, and liver, respectively, implying a potential role in the regulation of tissue differentiation or the maintenance of tissue identity."

According to the news reporters, the research concluded: "Overall, our results expand the number of tilapia miRNAs, and the discovery of miRNAs in tilapia genome contributes to a better understanding the role of miRNAs in regulating diverse biological processes."

For more information on this research see: MicroRNA repertoire for functional genome research in tilapia identified by deep sequencing. Molecular Biology Reports, 2014;41(8):4953-4963. Molecular Biology Reports can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Molecular Biology Reports - www.springerlink.com/content/0301-4851/)

Our news correspondents report that additional information may be obtained by contacting B. Yan, Shanghai Ocean Univ, Coll Informat Technol, Shanghai 201306, People's Republic of China. Additional authors for this research include Z.H. Wang, C.D. Zhu, J.T. Guo and J.L. Zhao (see also Life Science Research).

Keywords for this news article include: Shanghai, People's Republic of China, Asia, Life Science Research

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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