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New Globins Findings from University of Mazandaran Outlined (Novel superparamagnetic PFu@Fe3O4 conductive nanocomposite as a suitable host for...

September 10, 2014



New Globins Findings from University of Mazandaran Outlined (Novel superparamagnetic PFu@Fe3O4 conductive nanocomposite as a suitable host for hemoglobin immobilization)

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Proteins have been published. According to news reporting from Babol Sar, Iran, by NewsRx journalists, research stated, "A highly-sensitive hydrogen peroxide biosensor was fabricated by immobilization of hemoglobin (Hb) onto a biocompatible PFu@Fe3O4 nanocomposite/glassy carbon electrode (PFu@Fe3O4/GCE). The PFu@Fe3O4 nanocomposite was characterized by Fourier transform infrared spectra (FT-IR), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and vibrating sample magnetometer (VSM)."

The news correspondents obtained a quote from the research from the University of Mazandaran, "PFu@Fe3O4 nanocomposite which was synthesized via in situ polymerization at room temperature combined the advantages of superparamagnetic properties from Fe3O4 nanoparticles and conductive poly(furan) (PF) as the building block for fabrication of biosensor. The Hb immobilized on PFu@Fe3O4 nanocomposite retained its near-native conformations as characterized by the FT-IR. The heterogeneous electron transfer rate constant and Michaelis-Menten constant were calculated to be 0.76 s(-1) and 0.094 mM at pH 7.0, respectively."

According to the news reporters, the research concluded: "The proposed biosensor exhibited a linear response to hydrogen peroxide in the concentration ranging from 0.5 mu M to 350.0 mM with a correlation coefficient of 0.995, sensitivity of -0.089 mu A mu M-1 and detection limit of 0.31 mu M (S/N = 3), which could make it a promising third-generation biosensor for precise detection of hydrogen peroxide in the biological samples."

For more information on this research see: Novel superparamagnetic PFu@Fe3O4 conductive nanocomposite as a suitable host for hemoglobin immobilization. Sensors and Actuators B-Chemical, 2014;202():1200-1208. Sensors and Actuators B-Chemical can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also Proteins).

Our news journalists report that additional information may be obtained by contacting M. Baghayeri, Univ Mazandaran, Fac Chem, Dept. of Organ Polymer Chem, Babol Sar, Iran. Additional authors for this research include E.N. Zare and M.M. Lakouraj.

Keywords for this news article include: Babol Sar, Iran, Asia, Bioengineering, Bionanotechnology, Biosensing, Biotechnology, Blood Proteins, Chemicals, Chemistry, Hemoglobins, Hydrogen Peroxide, Nanobiotechnology, Nanotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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