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Investigators from University of Salento Target Multidrug Resistance (Nanomaterial-Induced Autophagy: A New Reversal MDR Tool in Cancer Therapy?)

September 10, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Drug Resistance. According to news reporting originating from Lecce, Italy, by NewsRx correspondents, research stated, "Most of the therapeutic strategies to counteract cancer imply killing of malignant cells."

Our news editors obtained a quote from the research from the University of Salento, "The most exploited cell death mechanism in cancer therapies is apoptosis, but recently, a lot of papers report that other mechanisms, mainly autophagy, could represent a new line of attack in the fight against cancer."

According to the news editors, the research concluded: "One of the limitations for the effectiveness of the approved clinical treatments is the phenomenon of multidrug resistance (MDR) which enables the cancer cells to develop resistance to therapy, especially for chemotherapy."

For more information on this research see: Nanomaterial-Induced Autophagy: A New Reversal MDR Tool in Cancer Therapy? Molecular Pharmaceutics, 2014;11(8):2527-2538. Molecular Pharmaceutics can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society -; Molecular Pharmaceutics -

The news editors report that additional information may be obtained by contacting E. Panzarini, Univ Salento, Dept. of Biol & Environm Sci & Technol DiSTeBA, I-73100 Lecce, Italy (see also Drug Resistance).

Keywords for this news article include: Lecce, Italy, Europe, Cancer, Genetics, Multidrug Resistance, Oncology, Therapy

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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