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Findings on Nanoparticles Detailed by Investigators at SASTRA University (Ellagic acid encapsulated chitosan nanoparticles as anti-hemorrhagic agent)

September 9, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Nanoparticles is the subject of a report. According to news reporting from Tamil Nadu, India, by NewsRx journalists, research stated, "Ellagic acid, a naturally occurring polyphenol was encapsulated in chitosan particles prepared by ionotropic gelation and characterized for its physicochemical properties. A maximum encapsulation efficiency of 49% was achieved."

The news correspondents obtained a quote from the research from SASTRA University, "The blood clotting time and clot retraction time were calculated for different concentrations of ellagic acid, chitosan and ellagic acid-encapsulated chitosan. A reduction of 34% in the clot time and 16.4% in the retraction time was observed in ellagic acid-encapsulated chitosan when compared with free ellagic acid at concentrations as low as 0.1 mg/mL. The physical blend in comparison to free ellagic acid displayed a reduction of 13.8% and 4.6% in the clotting time and retraction time respectively under similar conditions. This suggests that the encapsulation of ellagic acid favors thrombosis due to synergistic action of chitosan and ellagic acid on same molecular targets."

According to the news reporters, the research concluded: "This study demonstrates the potential of ellagic acid chitosan system as an effective anti-hemorrhagic system."

For more information on this research see: Ellagic acid encapsulated chitosan nanoparticles as anti-hemorrhagic agent. Carbohydrate Polymers, 2014;111():215-221. Carbohydrate Polymers can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier -; Carbohydrate Polymers -

Our news journalists report that additional information may be obtained by contacting L. Gopalakrishnan, SASTRA Univ, Sch Chem & Biotechnol, Center Nanotechnol & Adv Biomat CeNTAB, Thanjavur 613401, Tamil Nadu, India. Additional authors for this research include L.N. Ramana, S. Sethuraman and U.M. Krishnan (see also Nanoparticles).

Keywords for this news article include: Tamil Nadu, India, Asia, Emerging Technologies, Nanoparticle, Nanoparticles, Nanotechnology

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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