The news correspondents obtained a quote from the research, "Their amphiphilic character was evidenced by retention of the dyes: hydrophobic (Rose Bengal), amphiphilic (Brilliant Blue) and hydrophilic (Vitamin B12). The thermosensitive properties, more pronounced for ED-2003 crosslinked nanoparticles, were evidenced through absorbance variation, fluorescence and DLS measurements as a temperature function. The nanoparticles retain important amounts of anionic (diclofenac: 40-80 mg/g), cationic (methylene blue: 70-125 mg/g) and hydrophobic (alpha-tocopherol: 220-350 mg/g) drugs."
According to the news reporters, the research concluded: "The in vitro characterization of the drug polymer conjugates recommends the synthesized nanoparticles as supports for drug delivery."
For more information on this research see: Preparation and characterization of anionic pullulan thermoassociative nanoparticles for drug delivery. Carbohydrate Polymers, 2014;111():892-900. Carbohydrate Polymers can be contacted at:
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Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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