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Studies from Singapore National University Yield New Data on Nanoparticles (Conjugated-Polymer-Based Red-Emitting Nanoparticles for Two-Photon...

August 15, 2014



Studies from Singapore National University Yield New Data on Nanoparticles (Conjugated-Polymer-Based Red-Emitting Nanoparticles for Two-Photon Excitation Cell Imaging with High Contrast)

By a News Reporter-Staff News Editor at Science Letter -- Fresh data on Nanoparticles are presented in a new report. According to news reporting from Singapore, Singapore, by NewsRx journalists, research stated, "Two-photon fluorescence microscopy is a widely used noninvasive bioimaging technique because of unique advantages such as a large penetration depth and 3D mapping capability. Ideal two-photon fluorophores require large two-photon absorption cross sections and red emission with high quantum yields."

The news correspondents obtained a quote from the research from Singapore National University, "Here we report red-emitting-dye-doped conjugated polymer nanoparticles that display high two-photon excitation brightness. In these nanoparticles, conjugated polymer (PFV) was chosen as a two-photon light-harvesting material, and red-emitting dyes (MgPc and Nile red) were chosen as the energy acceptors and red-emitting materials. Two-photon excitation fluorescence of MgPc and Nile red was enhanced by up to similar to 53 and similar to 240 times, respectively. We have successfully demonstrated the application of these conjugated polymer-based nanoparticles in two-photon excitation cancer cell imaging with an excellent contrast ratio."

According to the news reporters, the research concluded: "This concept could become a general approach to the preparation of two-photon excitation red-emitting materials for deep-tissue live-cell imaging with high contrast."

For more information on this research see: Conjugated-Polymer-Based Red-Emitting Nanoparticles for Two-Photon Excitation Cell Imaging with High Contrast. Langmuir, 2014;30(26):7623-7627. Langmuir can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)

Our news journalists report that additional information may be obtained by contacting S. Li, Singapore National University, Dept. of Chem, Singapore 117543, Singapore. Additional authors for this research include X.Q. Shen, L. Li, P.Y. Yuan, Z.P. Guan, S.Q. Yao and Q.H. Xu (see also Nanoparticles).

Keywords for this news article include: Asia, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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