Study Results from Chinese Academy of Medical Sciences Update Understanding of Nanomaterials (Toxicity of inorganic nanomaterials in biomedical imaging)
By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Nanomaterials. According to news reporting originating in Beijing, People's Republic of China, by NewsRx journalists, research stated, "Inorganic nanoparticles have shown promising potentials as novel biomedical imaging agents with high sensitivity, high spatial and temporal resolution. To translate the laboratory innovations into clinical applications, their potential toxicities are highly concerned and have to be evaluated comprehensively both in vitro and in vivo before their clinical applications."
The news reporters obtained a quote from the research from the Chinese Academy of Medical Sciences, "In this review, we first summarized the in vivo and in vitro toxicities of the representative inorganic nanoparticles used in biomedical imagings. Then we further discuss the origin of nanotoxicity of inorganic nanomaterials, including ROS generation and oxidative stress, chemical instability, chemical composition, the surface modification, dissolution of nanoparticles to release excess free ions of metals, metal redox state, and left-over chemicals from synthesis, etc."
According to the news reporters, the research concluded: "We intend to provide the readers a better understanding of the toxicology aspects of inorganic nanomaterials and knowledge for achieving optimized designs of safer inorganic nanomaterials for clinical applications."
For more information on this research see: Toxicity of inorganic nanomaterials in biomedical imaging. Biotechnology Advances, 2014;32(4):727-743. Biotechnology Advances can be contacted at: Pergamon-Elsevier Science Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. (Elsevier - www.elsevier.com; Biotechnology Advances - www.elsevier.com/wps/product/cws_home/525455)
Our news correspondents report that additional information may be obtained by contacting J.X. Li, Chinese Academy Med Sci, Beijing 100021, People's Republic of China. Additional authors for this research include X.L. Chang, X.X. Chen, Z.J. Gu, F. Zhao, Z.F. Chai and Y.L. Zhao (see also Nanomaterials).
Keywords for this news article include: Asia, Beijing, Nanoparticle, Nanotechnology, Emerging Technologies, People's Republic of China
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