Target: certification of an oxygen carrier as a Class III medical product
Owing to their incidence rate, complexity and poor prognosis, the two diseases constitute a huge challenge in both in terms of their socio-economic impact and the associated intensive medical care, and incur unacceptably high mortality rates, despite progress made in intensive medicine. In
The approach adopted here by Sangui, ECCPS and TransMIT presupposes that self-perpetuating septic shock, that has so far been highly resistant to treatment, can be interrupted by Sangui's artificial haemoglobin-based oxygen carrier, which would ultimately lower mortality rates. The preclinical trials at ECCPS which are now approved aim to investigate the effect of various haemoglobin preparations on the oxygen supply of a number of organs in septic shock and ARDS models. The research alliance has devised a plan which uses a preparation similar to Granulox provided by Sangui and will work towards certification as a Class III medical device if the approach proves its worth and is successful.
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