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Research Data from Singapore National University Update Understanding of Drug Delivery Systems (Drug delivery vehicles on a nano-engineering...

August 13, 2014



Research Data from Singapore National University Update Understanding of Drug Delivery Systems (Drug delivery vehicles on a nano-engineering perspective)

By a News Reporter-Staff News Editor at Biotech Week -- Data detailed on Drugs and Therapies have been presented. According to news originating from Singapore, Singapore, by NewsRx correspondents, research stated, "Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical tools for not only modulation of pharmacological drug release profile but also specific targeting of diseased tissues."

Our news journalists obtained a quote from the research from Singapore National University, "Until now, encapsulation of anti-cancer molecules such as paclitaxel, vincristin and doxorubicin has been the main target of nDDS, whereby liposomes and polymer-drug conjugates remained as the most popular group of nDDS used for this purpose. The success reached by these nanocarriers can be imitated by careful selection and optimization of the different factors that affect drug release profile (i.e. type of biomaterial, size, system architecture, and biodegradability mechanisms) along with the selection of an appropriate manufacture technique that does not compromise the desired release profile, while it also offers possibilities to scale up for future industrialization."

According to the news editors, the research concluded: "This review focuses from an engineering perspective on the different parameters that should be considered before and during the design of new nDDS, and the different manufacturing techniques available, in such a way to ensure success in clinical application."

For more information on this research see: Drug delivery vehicles on a nano-engineering perspective. Materials Science & Engineering C-Materials for Biological Applications, 2014;41():178-195. Materials Science & Engineering C-Materials for Biological Applications can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Drugs and Therapies).

The news correspondents report that additional information may be obtained from B. Felice, Singapore National University, Dept. of Mech Engn, Singapore 138602, Singapore. Additional authors for this research include M.P. Prabhakaran, A.P. Rodriguez and S. Ramakrishna.

Keywords for this news article include: Asia, Engineering, Drugs and Therapies, Drug Delivery Systems

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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