Reports from University of British Columbia Provide New Insights into Drug Delivery Systems (A review of nanocellulose as a novel vehicle for drug delivery)
By a News Reporter-Staff News Editor at Biotech Week -- Research findings on Drugs and Therapies are discussed in a new report. According to news reporting originating in Vancouver, Canada, by NewsRx journalists, research stated, "The current state of research into nanocellulose in drug delivery is reviewed in this article. There are three types of nanocellulose: cellulose nanocrystals (CNC), cellulose nanofibrils (CNF) and bacterial cellulose (BC), all of which may be produced in suitable amounts at reasonable cost."
The news reporters obtained a quote from the research from the University of British Columbia, "All three have been investigated as drug delivery vehicles with CNC and CNF reported to bind and release some water-soluble drugs via ionic interactions whereas BC has been used to release drugs from flexible membranes. The rationale for using nanocellulose is the high surface area-to-volume ratio of the material that may enable high levels of drug binding at the surface. All forms of nanocellulose can be chemically modified to expand the range of drugs that may bind to the surface. Most studies are academic in nature and have not focused on formulating specific drugs for specific disease applications. Furthermore, there are few studies that have investigated the assumed biocompatibility or fate of nanocellulose in vivo. Arguably, a logical first application might be for wound dressings in which a nanocellulose-based antibiotic formulation could provide a controlled drug release aspect uncomplicated by internal biocompatibility or clearance concerns."
According to the news reporters, the research concluded: "The prospects for further research into nanocelluloses in drug delivery are discussed."
For more information on this research see: A review of nanocellulose as a novel vehicle for drug delivery. Nordic Pulp & Paper Research Journal, 2014;29(1):105-118. Nordic Pulp & Paper Research Journal can be contacted at: Ab Svensk Papperstidning, C, O Spci, Box 5515, SE114 85 Stockholm, Sweden (see also Drugs and Therapies).
Our news correspondents report that additional information may be obtained by contacting D.V. Plackett, University of British Columbia, Fac Pharmaceut Sci, Vancouver, BC V6T 1Z3, Canada. Additional authors for this research include K. Letchford, J.K. Jackson and H.M. Burt.
Keywords for this news article include: Canada, Vancouver, British Columbia, Drugs and Therapies, Drug Delivery Systems, North and Central America
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