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Reports from Division of Biotechnology Add New Data to Findings in Carboxylic Ester Hydrolases (Mycelium-Bound Lipase from a Locally Isolated Strain...

August 12, 2014

Reports from Division of Biotechnology Add New Data to Findings in Carboxylic Ester Hydrolases (Mycelium-Bound Lipase from a Locally Isolated Strain of Geotrichum candidum)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Enzymes and Coenzymes. According to news reporting from Kuala Lumpur, Malaysia, by NewsRx journalists, research stated, "Mycelium-bound lipase (MBL), from a locally isolated Geotrichum candidum strain, was produced and characterized as a natural immobilized lipase. A time course study of its lipolytic activity in 1 L liquid broth revealed the maximum MBL activity at 4 h for mycelium cells harvested after 54 h. The yield and specific activity of MBL were 3.87 g/L dry weight and 508.33 U/g protein, respectively, while less than 0.2 U/mL lipase activity was detected in the culture supernatant."

The news correspondents obtained a quote from the research from the Division of Biotechnology, "Prolonged incubation caused release of the bound lipase into the growth medium. The growth pattern of G. candidum, and production and properties of MBL were not affected by the scale. The stability of mycelia harboring lipase (MBL), harvested and lyophilized after 54 h, studied at 4 degrees C depicted a loss of 4.3% and 30% in MBL activity after 1 and 8 months, while the activity of free lipase was totally lost after 14 days of storage. The MBL from G. candidum displayed high substrate selectivity for unsaturated fatty acids containing a cis-9 double bond, even in crude form."

According to the news reporters, the research concluded: "This unique specificity of MBL could be a direct, simple and inexpensive way in the fats and oil industry for the selective hydrolysis or transesterification of cis-9 fatty acid residues in natural triacylglycerols."

For more information on this research see: Mycelium-Bound Lipase from a Locally Isolated Strain of Geotrichum candidum. Molecules, 2014;19(6):8556-8570. Molecules can be contacted at: Mdpi Ag, Postfach, Ch-4005 Basel, Switzerland. (Springer -; Molecules -

Our news journalists report that additional information may be obtained by contacting J.L. Loo, Malaysia Agr Res & Dev Inst, Div Biotechnol, Kuala Lumpur 50774, Malaysia. Additional authors for this research include A. Khoramnia, O.M. Lai, K. Long and H.M. Ghazali (see also Enzymes and Coenzymes).

Keywords for this news article include: Asia, Lipase, Malaysia, Kuala Lumpur, Enzymes and Coenzymes, Carboxylic Ester Hydrolases

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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