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Recent Findings in Imino Pyranoses Described by Researchers from Department of Pharmaceutical Engineering [Response surface optimized extraction of...

August 12, 2014



Recent Findings in Imino Pyranoses Described by Researchers from Department of Pharmaceutical Engineering [Response surface optimized extraction of 1-deoxynojirimycin from mulberry leaves (Morus alba L.) and preparative separation with resins]

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Imino Pyranoses. According to news reporting originating in Beijing, People's Republic of China, by NewsRx journalists, research stated, "In the present study, the extraction technology and preparative separation of 1-deoxynojirimycin from mulberry leaves were systematically investigated. Four extraction parameters (ethanol concentration, extraction temperature, extraction time and ratio of solvent to sample) were explored by response surface methodology (RSM)."

The news reporters obtained a quote from the research from the Department of Pharmaceutical Engineering, "The results indicated that the maximal yield of 1-deoxynojirimycin was achieved with an ethanol concentration of 55%, extraction temperature of 80 C, extraction time of 1.2 h and ratio of solvent to sample of 12:1. The extraction yield under these optimum conditions was found to be 256 mg/100 g dry mulberry leaves. A column packed with a selected resin was used to perform dynamic adsorption and desorption tests to optimize the separation process. The results show that the preparative separation of 1-deoxynojirimycin from mulberry leaves can be easily and effectively done by adopting 732 resin."

According to the news reporters, the research concluded: "732 resin is the most appropriate for the separation of 1-deoxynojirimycin from other components in mulberry leaves extracts, and its adsorption behavior can be described with Langmuir isotherms and a two-step adsorption kinetics model. The recovery and purity of 1-deoxynojirimycin in the final product were 90.51% and 15."

For more information on this research see: Response surface optimized extraction of 1-deoxynojirimycin from mulberry leaves (Morus alba L.) and preparative separation with resins. Molecules, 2014;19(6):7040-56. (Springer - www.springer.com; Molecules - www.springerlink.com/content/1420-3049/)

Our news correspondents report that additional information may be obtained by contacting T. Wang, Dept. of Pharmaceutical Engineering, Beijing Institute of Petro-chemical Technology, Beijing 102617, People's Republic of China. Additional authors for this research include C.Q. Li, H. Zhang and J.W Li (see also Imino Pyranoses).

Keywords for this news article include: Asia, Beijing, Imino Pyranoses, 1 Deoxynojirimycin, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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