News Column

Patent Application Titled "Medical Devices and Related Methods" Published Online

August 11, 2014



By a News Reporter-Staff News Editor at Biotech Business Week -- According to news reporting originating from Washington, D.C., by NewsRx journalists, a patent application by the inventors Holman, Thomas J. (Princeton, MN); Shippy, III, James Lee (Wilmington, NC); Ali, Afsar (Maple Grove, MN), filed on March 20, 2014, was made available online on July 31, 2014 (see also Biotechnology Companies).

The assignee for this patent application is Boston Scientific Scimed, Inc.

Reporters obtained the following quote from the background information supplied by the inventors: "Balloon catheters can be used for a variety of medical procedures such as, for example, to widen an occluded body vessel, as in angioplasty, to position a medical device, such as a stent or a graft, or to selectively block a passageway. A balloon catheter may include an inflatable and deflatable balloon positioned on a catheter body. Initially, the balloon is folded around the catheter body to reduce the radial profile of the balloon catheter for easy insertion into the body.

"During use, for example, in angioplasty, the folded balloon can be positioned at a location in a vessel occluded by a stenosis by threading the balloon catheter through a guide catheter and over a guide wire emplaced in the body. The balloon is then inflated, e.g., by introducing a fluid into the interior of the balloon. Inflating the balloon can radially expand the stenosis to permit increased blood flow through the vessel. After expanding the stenosis, the balloon is deflated and withdrawn from the body."

In addition to obtaining background information on this patent application, NewsRx editors also obtained the inventors' summary information for this patent application: "In one aspect of the invention, a method includes applying a material to an at least partially inflated medical balloon, folding the medical balloon, and, after folding the medical balloon, removing at least some of the material exposed about an outer surface of the folded medical balloon.

"In another aspect of the invention, a method includes applying a material to a medical balloon and removing the material overlying one or more fold regions of the medical balloon. The material applied to the medical balloon has a coefficient of friction different than a coefficient of friction of the medical balloon.

"In a further aspect of the invention, a balloon catheter includes a balloon folded about a catheter shaft. The folded balloon includes outer fold regions that are substantially exposed about an outer surface of the folded balloon and inner fold regions that are substantially unexposed about the outer surface of the folded balloon. The inner fold regions are coated with a material and the outer fold regions are substantially free of the material.

"Embodiments can include one or more of the following features.

"In some embodiments, after removing the material, one or more inner fold regions of the balloon include the material thereon, and one or more outer fold regions of the balloon include substantially none of the material thereon.

"In some embodiments, upon inflating the medical balloon, one or more regions of an outer surface of the inflated medical balloon include the material thereon and one or more regions of the outer surface of the inflated medical balloon include substantially none of the material thereon.

"In some embodiments, the material has a coefficient of friction different than (e.g., greater than or less than) a coefficient of friction of the medical balloon.

"In certain embodiments, the material is a lubricant.

"In some embodiments, applying the material to the medical balloon includes using one or more of the following material application techniques: spraying, painting, dip coating, and pad printing.

"In certain embodiments, removing the material includes applying laser energy (e.g., laser energy has a wavelength of about 157 nm to about 355 nm) to the material.

"In some embodiments, the method includes passing the laser energy through a masking device.

"In certain embodiments, removing the material includes removing the material from substantially the entire surface of a portion of the folded balloon.

"In some embodiments, the material is removed from a body portion of the folded balloon.

"In certain embodiments, the material is removed from substantially an entire exposed outer surface of the folded balloon.

"In some embodiments, the method includes deflating the medical balloon after applying the material to the medical balloon.

"In certain embodiments, the method includes disposing an implantable medical endoprosthesis about the folded medical balloon.

"In some embodiments, the implantable medical endoprosthesis is disposed about the folded medical balloon after the material is removed from the medical balloon.

"In certain embodiments, the implantable medical endoprosthesis is a stent.

"In some embodiments, the method includes folding the medical balloon.

"In certain embodiments, after folding the medical balloon, one or more outer fold regions are exposed about an outer surface of the folded medical balloon and one or more inner fold regions are substantially unexposed about the outer surface of the folded medical balloon.

"In some embodiments, the one or more fold regions include one or more inner fold regions of the medical balloon.

"In certain embodiments, the one or more fold regions include one or more outer fold regions of the medical balloon.

"In some embodiments, after removing the material, one or more inner fold regions of the balloon include the material thereon, and one or more outer fold regions of the balloon include substantially none of the material thereon.

"In certain embodiments, after removing the material, one or more outer fold regions of the balloon include the material thereon, and one or more inner fold regions of the balloon include substantially none of the material thereon.

"In some embodiments, upon inflating the medical balloon, one or more regions of an outer surface of the inflated medical balloon include the material thereon and one or more regions of the outer surface of the inflated medical balloon include substantially none of the material thereon.

"In certain embodiments, the medical balloon is at least partially inflated when the material is applied to the medical balloon.

"In some embodiments, the method includes deflating the inflatable medical balloon after removing the material from the medical balloon.

"In certain embodiments, the material is removed from substantially only the one or more fold regions of the medical balloon.

"In some embodiments, the method further includes treating the medical balloon to form the one or more fold regions.

"In certain embodiments, the medical balloon is treated before removing the material from the medical balloon.

"In some embodiments, treating the medical balloon includes applying laser energy to the inflatable medical balloon.

"In certain embodiments, upon inflating the balloon, both the inner and outer fold regions are exposed about an outer surface of the inflated balloon.

"Embodiments can include one or more of the following advantages.

"In some embodiments, the balloon is configured such that, when the balloon is deflated and folded, substantially only regions having a relatively high coefficient of friction is/are exposed about the outer surface of the balloon, and such that, when the balloon is inflated, both the regions having a relatively high coefficient of friction and regions having a relatively low coefficient of friction are exposed about the outer surface of the balloon. As a result of this configuration, the balloon can help to restrain (e.g., axially and/or circumferentially restrain) the implantable medical endoprosthesis thereon when the balloon is delivered through a body vessel in the deflated state, and can help to reduce the amount of friction experienced by the balloon as the balloon is removed from the deployed medical endoprosthesis after being inflated to deploy the implantable medical endoprosthesis within the body vessel.

"In certain embodiments, the balloon is configured such that, when the balloon is deflated and folded, substantially only the regions having a relatively low coefficient of friction is/are exposed about the outer surface of the balloon, and such that, when the balloon is inflated, both the regions having a relatively low coefficient of friction and regions having a relatively high coefficient of friction are exposed about the outer surface of the balloon. This configuration can help to reduce the friction encountered by the folded balloon as it is delivered through the body vessel, and can help to increase frictional resistance between the balloon and the body vessel wall, and thus stabilize the balloon, when the balloon is inflated within the body vessel, e.g., during an angioplasty procedure.

"In some embodiments, laser energy is applied to desired regions of the material (e.g., the lubricant) to remove the material from the balloon surface. Using laser energy to remove the material can, for example, allow the material to be removed with sufficient accuracy to ensure that material is removed from substantially only desired regions of the balloon surface. In certain embodiments, the material (e.g., the lubricant) is cured to help prevent the material remaining on the balloon surface from migrating into those regions of the balloon surface from which the material was removed.

"Other aspects, features, and advantages will be apparent from the description, drawings, and claims.

DESCRIPTION OF DRAWINGS

"FIG. 1 is a perspective view of an embodiment of a balloon catheter in a deflated state.

"FIG. 2 is a cross-sectional view taken along line 2-2 in FIG. 1.

"FIG. 3 is a perspective view of an embodiment of a balloon catheter in an inflated state.

"FIG. 4 is a cross-sectional view taken along line 4-4 in FIG. 3.

"FIGS. 5A-5E illustrate an embodiment of a method of using a balloon catheter.

"FIGS. 6A-6G illustrate an embodiment of a method of manufacturing a balloon catheter.

"FIG. 7 is a perspective view of an embodiment of a balloon catheter in an uninflated state.

"FIG. 8 is a cross-sectional view taken along line 8-8 in FIG. 7.

"FIG. 9 is a perspective view of an embodiment of a balloon catheter in an inflated state.

"FIG. 10 is a cross-sectional view taken along line 10-10 in FIG. 9.

"FIGS. 11A-11F illustrate a method of manufacturing a balloon catheter.

"Like reference symbols in the various drawings indicate like elements."

For more information, see this patent application: Holman, Thomas J.; Shippy, III, James Lee; Ali, Afsar. Medical Devices and Related Methods. Filed March 20, 2014 and posted July 31, 2014. Patent URL: http://appft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.html&r=1414&p=29&f=G&l=50&d=PG01&S1=20140724.PD.&OS=PD/20140724&RS=PD/20140724

Keywords for this news article include: Surgery, Stenosis, Angiology, Lubricants, Angioplasty, Endoprosthesis, Catheterization, Medical Devices, Balloon Catheter, Surgical Technology, Biotechnology Companies, Boston Scientific Scimed Inc..

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Business Week


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