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Investigators from Pontifical Catholic University Have Reported New Data on Membrane Proteins (Toward atomic force microscopy and mass spectrometry...

August 12, 2014



Investigators from Pontifical Catholic University Have Reported New Data on Membrane Proteins (Toward atomic force microscopy and mass spectrometry to visualize and identify lipid rafts in plasmodesmata)

By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Membrane Proteins is now available. According to news reporting from Santiago, Chile, by NewsRx journalists, research stated, "Plant cell-to-cell communication is mediated by nanopores called plasmodesmata (PDs) which are complex structures comprising plasma membrane (PM), highly packed endoplasmic reticulum and numerous membrane proteins. Although recent advances on proteomics have led to insights into mechanisms of transport, there is still an inadequate characterization of the lipidic composition of the PM where membrane proteins are inserted."

The news correspondents obtained a quote from the research from Pontifical Catholic University, "It has been postulated that PDs could be formed by lipid rafts, however no structural evidence has shown to visualize and analyse their lipid components. In this perspective article, we discuss proposed experiments to characterize lipid rafts and proteins in the PDs. By using atomic force microscopy (AFM) and mass spectrometry (MS) of purified PD vesicles it is possible to determine the presence of lipid rafts, specific bound proteins and the lipidomic profile of the PD under physiological conditions and after changing transport permeability. In addition, MS can determine the stoichiometry of intact membrane proteins inserted in lipid rafts."

According to the news reporters, the research concluded: "This will give novel insights into the role of membrane proteins and lipid rafts on the PD structure."

For more information on this research see: Toward atomic force microscopy and mass spectrometry to visualize and identify lipid rafts in plasmodesmata. Frontiers in Plant Science, 2014;5():1-9. Frontiers in Plant Science can be contacted at: Frontiers Research Foundation, PO Box 110, Lausanne, 1015, Switzerland (see also Membrane Proteins).

Our news journalists report that additional information may be obtained by contacting P.A. Naulin, Pontifical Catholic University, Fac Biol Sci, Dept. of Physiol, Santiago 8331150, Chile. Additional authors for this research include N.A. Alveal and N.P. Barrera.

Keywords for this news article include: Chile, Santiago, South America, Cell Membrane, Plasmodesmata, Membrane Proteins, Cellular Structures, Intercellular Junctions

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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