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Findings on DNA Research Detailed by Researchers at Shanxi Normal University (Phosphorescent quantum dots/doxorubicin nanohybrids based on...

August 12, 2014



Findings on DNA Research Detailed by Researchers at Shanxi Normal University (Phosphorescent quantum dots/doxorubicin nanohybrids based on photoinduced electron transfer for detection of DNA)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on DNA Research. According to news reporting out of Linfen, People's Republic of China, by NewsRx editors, research stated, "MPA-capped Mn-doped ZnS QDs/DXR nanohybrids (MPA: 3-mercaptopropionic acid; QDs: quantum dots; DXR: cetyltrimethyl ammonium bromide) were constructed via photoinduced electron transfer (PIET) and then used as a room-temperature phosphorescence (RTP) probe for detection of DNA. DXR as a quencher will quench the RTP of Mn-doped ZnS QDs via PIET, thereby forming Mn-doped ZnS QDs/DXR nanohybrids and storing RTP."

Our news journalists obtained a quote from the research from Shanxi Normal University, "With the addition of DNA, it will be inserted into DXR and thus DXR will be competitively desorbed from the surface of Mn-doped ZnS QDs, thereby releasing the RTP of Mn-doped ZnS QDs. Based on this, a new method for DNA detection was built. The sensor for DNA has a detection limit of 0.039 mg L(-1) and a linear range from 0.1 to 14 mg L(-1). The present QDs-based RTP method does not need deoxidants or other inducers as required by conventional RTP detection methods, and avoids interference from autofluorescence and the scattering light of the matrix that are encountered in spectrofluorometry."

According to the news editors, the research concluded: "Therefore, this method can be used to detect the DNA content in body fluid."

For more information on this research see: Phosphorescent quantum dots/doxorubicin nanohybrids based on photoinduced electron transfer for detection of DNA. Biosensors & Bioelectronics, 2014;59():300-6. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)

Our news journalists report that additional information may be obtained by contacting Y. Miao, Shanxi Normal University, Linfen 041004, People's Republic of China. Additional authors for this research include Z. Zhang, Y. Gong and G. Yan (see also DNA Research).

Keywords for this news article include: Asia, Linfen, DNA Research, Quantum Dots, Nanotechnology, Quantum Physics, Emerging Technologies, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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