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Findings from University Hospital in the Area of General Chemistry Described (Analysis of the endogenous human serum peptides by on-line extraction...

August 12, 2014



Findings from University Hospital in the Area of General Chemistry Described (Analysis of the endogenous human serum peptides by on-line extraction with restricted-access material and HPLC-MS/MS identification)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on General Chemistry. According to news reporting originating in Munich, Germany, by NewsRx journalists, research stated, "The selective extraction of endogenous serum peptides has been a challenge due to the high abundant proteins present in serum."

The news reporters obtained a quote from the research from University Hospital, "Here a simple on-line extraction of peptides from human serum using strong cation-exchange diol silica restricted-access materials (SCX-RAM) coupled with two-dimensional RP-RP liquid chromatography mass spectrometry was developed. The operation of the on-line extraction system is simple to use and does not need complex equipments."

According to the news reporters, the research concluded: "The two-dimensional RP-RP was proved to be orthogonal and efficient to separate peptides extracted from human serum."

For more information on this research see: Analysis of the endogenous human serum peptides by on-line extraction with restricted-access material and HPLC-MS/MS identification. Talanta, 2014;127():191-195. Talanta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Talanta - www.elsevier.com/wps/product/cws_home/525438)

Our news correspondents report that additional information may be obtained by contacting L.H. Hu, Univ Hosp Grosshadem, Inst Clin Chem, Lab BioSeparat, D-81366 Munich, Germany. Additional authors for this research include K.S. Boos, M.L. Ye and H.F. Zou (see also General Chemistry).

Keywords for this news article include: Munich, Europe, Germany, General Chemistry

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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