Findings from Radboud University Provides New Data on Bone Research (Self-healing hybrid nanocomposites consisting of bisphosphonated hyaluronan and calcium phosphate nanoparticles)
By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Bone Research have been published. According to news originating from Nijmegen, Netherlands, by NewsRx correspondents, research stated, "Non-covalent interactions are often regarded as insufficient to construct macroscopic materials of substantial integrity and cohesion. However, the low binding energy of such reversible interactions can be compensated by increasing their number to work in concert to create strong materials."
Our news journalists obtained a quote from the research from Radboud University, "Here we present the successful development of an injectable, cohesive nanocomposite hydrogel based on reversible bonds between calcium phosphate nanoparticles and bisphosphonate-functionalized hyaluronic acid. These nanocomposites display a capacity for self-healing as well as adhesiveness to mineral surfaces such as enamel and hydroxyapatite. Most importantly, these non-covalently cross-linked composites are surprisingly robust yet biodegradable upon extensive in vitro and in vivo testing and show bone interactive capacity evidenced by bone ingrowth into material remnants."
According to the news editors, the research concluded: "The herein presented method provides a new methodology for constructing nanoscale composites for biomedical applications, which owe their integrity to reversible bonds."
For more information on this research see: Self-healing hybrid nanocomposites consisting of bisphosphonated hyaluronan and calcium phosphate nanoparticles. Biomaterials, 2014;35(25):6918-6929. Biomaterials can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Biomaterials - www.elsevier.com/wps/product/cws_home/30392)
The news correspondents report that additional information may be obtained from M.R. Nejadnik, Radboud University, Medical Center, Dept. of Prevent & Restorat Dental, NL-6525 EX Nijmegen, Netherlands. Additional authors for this research include X. Yang, M. Bongio, H.S. Alghamdi, J. Van den Beucken, M.C. Huysmans, J.A. Jansen, J. Hilborn, D. Ossipov and S.C.G. Leeuwenburgh (see also Bone Research).
Keywords for this news article include: Europe, Anions, Nijmegen, Netherlands, Nanoparticle, Bone Research, Nanotechnology, Phosphoric Acids, Calcium Compounds, Calcium Phosphates, Inorganic Chemicals, Phosphorus Compounds, Emerging Technologies
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