Data on Tissue Engineering Reported by Researchers at Tohoku University (Myotube formation on gelatin nanofibers - multi-walled carbon nanotubes hybrid scaffolds)
By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Biomedicine and Biomedical Engineering have been published. According to news originating from Sendai, Japan, by NewsRx correspondents, research stated, "Engineering functional muscle tissue requires the formation of densely packed, aligned, and mature myotubes. To enhance the formation of aligned myotubes with improved contractibility, we fabricated aligned electrospun gelatin multi-walled carbon nanotubes (MWNTs) hybrid fibers that were used as scaffolds for the growth of myoblasts (C2C12)."
Our news journalists obtained a quote from the research from Tohoku University, "The MWNTs significantly enhanced myotube formation by improving the mechanical properties of the resulting fibers and upregulated the activation of mechanotransduction related genes. In addition, the fibers enhanced the maturation of the myotubes and the amplitude of the myotube contractions under electrical stimulation (ES)."
According to the news editors, the research concluded: "Such hybrid material scaffolds may be useful to direct skeletal muscle cellular organization, improve cellular functionality and tissue formation."
For more information on this research see: Myotube formation on gelatin nanofibers - multi-walled carbon nanotubes hybrid scaffolds. Biomaterials, 2014;35(24):6268-77. (Elsevier - www.elsevier.com; Biomaterials - www.elsevier.com/wps/product/cws_home/30392)
The news correspondents report that additional information may be obtained from S. Ostrovidov, WPI-Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan. Additional authors for this research include X. Shi, L. Zhang, X. Liang, S.B. Kim, T. Fujie, M. Ramalingam, M. Chen, K. Nakajima, F. Al-Hazmi, H. Bae, A. Memic and A. Khademhosseini (see also Biomedicine and Biomedical Engineering).
Keywords for this news article include: Asia, Tissue Engineering, Biomedicine and Biomedical Engineering, Japan, Sendai, Gelatin, Nanofiber, Fullerenes, Bioengineering, Nanotechnology, Scleroproteins, Carbon Nanotubes, Emerging Technologies.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC