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Data on Chalcogens Reported by Researchers at Washington University (Rapid quantification of oxygen tension in blood flow with a fluorine...

August 15, 2014



Data on Chalcogens Reported by Researchers at Washington University (Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Chalcogens. According to news originating from St. Louis, Missouri, by NewsRx correspondents, research stated, "We present a novel blood flow-enhanced-saturation-recovery (BESR) sequence, which allows rapid in vivo T1 measurement of blood for both (1)H and (19)F nuclei. BESR sequence is achieved by combining homogeneous spin preparation and time-of-flight image acquisition and therefore preserves high time efficiency and signal-to-noise ratio for (19)F imaging of circulating perfluorocarbon nanoparticles comprising a perfluoro-15-crown-5-ether core and a lipid monolayer (nominal size=250 nm)."

Our news journalists obtained a quote from the research from Washington University, "The consistency and accuracy of the BESR sequence for measuring T1 of blood was validated experimentally. With a confirmed linear response feature of (19)F R1 with oxygen tension in both salt solution and blood sample, we demonstrated the feasibility of the BESR sequence to quantitatively determine the oxygen tension within mouse left and right ventricles under both normoxia and hyperoxia conditions."

According to the news editors, the research concluded: "Thus, (19)F BESR MRI of circulating perfluorocarbon nanoparticles represents a new approach to noninvasively evaluate intravascular oxygen tension."

For more information on this research see: Rapid quantification of oxygen tension in blood flow with a fluorine nanoparticle reporter and a novel blood flow-enhanced-saturation-recovery sequence. Magnetic Resonance In Medicine, 2013;70(1):176-83. (Wiley-Blackwell - www.wiley.com/; Magnetic Resonance In Medicine - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1522-2594)

The news correspondents report that additional information may be obtained from L. Hu, Dept. of Physics, Washington University, St Louis, Missouri, United States. Additional authors for this research include J. Chen, X. Yang, S.D. Caruthers, G.M. Lanza and S.A Wickline (see also Chalcogens).

Keywords for this news article include: Missouri, St. Louis, Chalcogens, Nanoparticle, United States, Nanotechnology, Emerging Technologies, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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