Researchers' Work from University of Tennessee Focuses on Proinsulin [Selected Clinical, Biochemical, And Electrolyte Alterations In Anesthetized Captive Tigers (panthera Tigris) And Lions (panthera Leo)]
By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Peptide Proteins are presented in a new report. According to news reporting originating in Knoxville, Tennessee, by NewsRx journalists, research stated, "A prospective study to assess changes in selected plasma biochemistry and electrolyte values, plasma insulin and aldosterone concentrations, and electrocardiography (ECG) was performed on eight female captive tigers (Panthera tigris) and three lions (Panthera leo) undergoing general anesthesia for elective laparoscopic ovariectomy. Each animal was sedated with medetomidine (18-25 mu g/kg) and midazolam (0.06-0.1 mg/kg) intramuscularly, and anesthesia was induced with ketamine (1.9-3.5 mg/kg) intramuscularly and maintained with isoflurane."
The news reporters obtained a quote from the research from the University of Tennessee, "Venous blood samples were collected and analyzed for plasma biochemistry parameters and insulin and aldosterone concentrations. An ECG was recorded at the time of each blood sample collection. Mean plasma potassium, glucose, phosphorus, and aldosterone concentrations increased during anesthesia (P
According to the news reporters, the research concluded: "Based on these results, continuous monitoring of clinical and biochemical alterations during general anesthesia in large nondomestic felids is warranted, and consideration should be given to reversal of medetomidine in these animals should significant changes in electrolytes or ECG occur."
For more information on this research see: Selected Clinical, Biochemical, And Electrolyte Alterations In Anesthetized Captive Tigers (panthera Tigris) And Lions (panthera Leo). Journal of Zoo and Wildlife Medicine, 2014;45(2):328-334. Journal of Zoo and Wildlife Medicine can be contacted at: Amer Assoc Zoo Veterinarians, 581705 White Oak Road, Yulee, FL 32097, USA (see also Peptide Proteins).
Our news correspondents report that additional information may be obtained by contacting S. Reilly, University of Tennessee, Coll Vet Med, Dept. of Biomed & Diagnost Sci, Knoxville, TN 37996, United States. Additional authors for this research include R. Seddighi, J.C. Steeil, P. Sura, J.C. Whittemore, R.E. Gompf, S.B. Elliott and E.C. Ramsay.
Keywords for this news article include: Knoxville, Tennessee, Proinsulin, Aldosterone, Biochemical, Biochemistry, Electrolytes, United States, Peptide Hormones, Peptide Proteins, Inorganic Chemicals, Adrenal Cortex Hormones, North and Central America, 11-Hydroxycorticosteroids
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