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Researchers from Arizona State University Report on Findings in Cell Surface Extensions (Food grade titanium dioxide disrupts intestinal brush border...

September 2, 2014



Researchers from Arizona State University Report on Findings in Cell Surface Extensions (Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation)

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators discuss new findings in Cell Surface Extensions. According to news originating from Tempe, Arizona, by NewsRx correspondents, research stated, "Bulk-and nano-scale titanium dioxide (TiO2) has found use in human food products for controlling color, texture, and moisture. Once ingested, and because of their small size, nano-scale TiO2 can interact with a number of epithelia that line the human gastrointestinal tract."

Our news journalists obtained a quote from the research from Arizona State University, "One such epithelium responsible for nutrient absorption is the small intestine, whose constituent cells contain microvilli to increase the total surface area of the gut. Using a combination of scanning and transmission electron microscopy it was found that food grade TiO2 (E171 food additive coded) included similar to 25 % of the TiO2 as nanoparticles (NPs;

According to the news editors, the research concluded: "These data indicate that food grade TiO2 exposure resulted in the loss of microvilli from the Caco-2(BBe1) cell system due to a biological response, and not simply a physical artifact of in vitro exposure."

For more information on this research see: Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation. Cell Biology and Toxicology, 2014;30(3):169-188. Cell Biology and Toxicology can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer - www.springer.com; Cell Biology and Toxicology - www.springerlink.com/content/0742-2091/)

The news correspondents report that additional information may be obtained from J.J. Faust, Arizona State University, Sch Sustainable Engn & Built Environm, Tempe, AZ 85287, United States. Additional authors for this research include K. Doudrick, Y. Yang, P. Westerhoff and D.G. Capco (see also Cell Surface Extensions).

Keywords for this news article include: Tempe, Arizona, Chemicals, Chemistry, Microvilli, Light Metals, Nanoparticle, United States, Nanotechnology, Titanium Dioxide, Emerging Technologies, Cell Surface Extensions, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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