News Column

Investigators at National Cancer Institute Detail Findings in Cell Biology (Deep Imaging: the next frontier in microscopy)

September 2, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Cell Biology have been presented. According to news reporting originating from Bethesda, Maryland, by NewsRx correspondents, research stated, "The microscope is the quintessential tool for discovery in cell biology. From its earliest incarnation as a tool to make the unseen visible, microscopes have been at the center of most revolutionizing developments in cell biology, histology and pathology."

Our news editors obtained a quote from the research from National Cancer Institute, "Major quantum leaps in imaging involved the dramatic improvements in resolution to see increasingly smaller structures, methods to visualize specific molecules inside of cells and tissues, and the ability to peer into living cells to study dynamics of molecules and cellular structures. The latest revolution in microscopy is Deep Imaging-the ability to look at very large numbers of samples by high-throughput microscopy at high spatial and temporal resolution. This approach is rooted in the development of fully automated high-resolution microscopes and the application of advanced computational image analysis and mining methods. Deep Imaging is enabling two novel, powerful approaches in cell biology: the ability to image thousands of samples with high optical precision allows every discernible morphological pattern to be used as a read-out in large-scale imaging-based screens, particularly in conjunction with RNAi-based screening technology; in addition, the capacity to capture large numbers of images, combined with advanced computational image analysis methods, has also opened the door to detect and analyze very rare cellular events."

According to the news editors, the research concluded: "These two applications of Deep Imaging are revolutionizing cell biology."

For more information on this research see: Deep Imaging: the next frontier in microscopy. Histochemistry and Cell Biology, 2014;142(2):125-131. Histochemistry and Cell Biology can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Histochemistry and Cell Biology -

The news editors report that additional information may be obtained by contacting V. Roukos, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States (see also Cell Biology).

Keywords for this news article include: Bethesda, Maryland, Cell Biology, United States, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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