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Data from Southeast University Advance Knowledge in Extracellular Space (Fabrication of Hydrogel with Cell Adhesive Micropatterns for Mimicking the...

September 2, 2014



Data from Southeast University Advance Knowledge in Extracellular Space (Fabrication of Hydrogel with Cell Adhesive Micropatterns for Mimicking the Oriented Tumor-Associated Extracellular Matrix)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Extracellular Space have been published. According to news originating from Suzhou, People's Republic of China, by NewsRx correspondents, research stated, "For mimicking the fibrous extracellular matrix (ECM), a facile method for patterning anticell adhesive substrate was novelly applied on agarose hydrogel. Without using masks or templates for etching, we applied the magnetic field-induced colloidal assembly of magnetic nanoparticles on the flat agarose hydrogel to form cell-adhesive micropatterns."

Our news journalists obtained a quote from the research from Southeast University, "Meanwhile, tuning the hydrogel substrate's modulus to fit real tissue was experimentally demonstrated. Magnetic nanobeads were also assembled on this hydrogel surface and formed more complete and regular patterns."

According to the news editors, the research concluded: "The patterned hydrogel substrate could actually influence behaviors of different cancer cells, including adhesion, growth, and migration."

For more information on this research see: Fabrication of Hydrogel with Cell Adhesive Micropatterns for Mimicking the Oriented Tumor-Associated Extracellular Matrix. ACS Applied Materials & Interfaces, 2014;6(14):10963-10968. ACS Applied Materials & Interfaces can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Applied Materials & Interfaces - www.pubs.acs.org/journal/aamick)

The news correspondents report that additional information may be obtained from Z.B. Guo, Southeast Univ, Suzhou Key Lab Biomed Mat & Technol, Res Inst, Suzhou 215123, People's Republic of China. Additional authors for this research include K. Hu, J.F. Sun, T.Z. Zhang, Q.Y. Zhang, L. Song, X.Z. Zhang and N. Gu (see also Extracellular Space).

Keywords for this news article include: Asia, Suzhou, Extracellular Space, Extracellular Matrix, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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