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New Nanoparticles Study Results Reported from Johannes Gutenberg-University (The "Needle in the Haystack" Makes the Difference: Linear and...

August 29, 2014



New Nanoparticles Study Results Reported from Johannes Gutenberg-University (The "Needle in the Haystack" Makes the Difference: Linear and Hyperbranched Polyglycerols with a Single Catechol Moiety for Metal Oxide Nanoparticle Coating)

By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Nanoparticles. According to news originating from Mainz, Germany, by NewsRx correspondents, research stated, "Multifunctional linear (CA-linPG) and hyperbranched polyglycerols (CA-hbPG) bearing a single catechol unit were synthesized by use of an acetonide-protected catechol initiator for the anionic polymerization of ethoxyethyl glycidyl ether (EEGE) and glycidol, respectively. A key feature for the synthesis of the hyperbranched structures was a selective, partial acetal deprotection step."

Our news journalists obtained a quote from the research from Johannes Gutenberg-University, "The single catechol unit among a large number of aliphatic 1,2- and 1,3-diol moieties (i.e., the 'needle in the haystack') in both linear and hyperbranched polyglycerols permits dispersion of transition metal oxide nanoparticles in brine, as demonstrated for manganese oxide (MnO) nanoparticles. Molecular weights of the single catechol bearing PGs ranged from 950 to 2350 g.mol(-1) for CA-linPG and from 3750 to 5750 g.mol(-1) for CA-hbPG with narrow and monomodal molecular weight distributions (M-w/M-n < 1.23 for linPG and M-w/M-n, = 1.22-1.48 for hbPG). Both C-linPGs and C-hbPGs are suitable hydrophilic capping agents to generate highly hydroxyl-functional nanoparticles with hydrophilic PG shell. The PG content of the polymer-coated MnO nanoparticles (diameter 17 nm) was in the range 21-54 wt %, as determined via TGA."

According to the news editors, the research concluded: "The MnO nanoparticles with a hydrophilic, multifunctional polyglycerol shell may represent a promising alternative to iron oxide or gadolinium contrast agents for MRI."

For more information on this research see: The "Needle in the Haystack" Makes the Difference: Linear and Hyperbranched Polyglycerols with a Single Catechol Moiety for Metal Oxide Nanoparticle Coating. Macromolecules, 2014;47(14):4557-4566. Macromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Macromolecules - www.pubs.acs.org/journal/mamobx)

The news correspondents report that additional information may be obtained from A. Thomas, Johannes Gutenberg Univ Mainz, Inst Phys Chem, D-55099 Mainz, Germany. Additional authors for this research include H. Bauer, A.M. Schilmann, K. Fischer, W. Tremel and H. Frey (see also Nanoparticles).

Keywords for this news article include: Mainz, Europe, Germany, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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