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New Materials Science and Physical Chemistry Study Findings Have Been Reported by Researchers at University of Washington (Europium-Complex-Grafted...

August 29, 2014



New Materials Science and Physical Chemistry Study Findings Have Been Reported by Researchers at University of Washington (Europium-Complex-Grafted Polymer Dots for Amplified Quenching and Cellular Imaging Applications)

By a News Reporter-Staff News Editor at Science Letter -- Investigators discuss new findings in Science. According to news originating from Seattle, Washington, by NewsRx correspondents, research stated, "We report on a europium-complex-grafted polymer for preparing stable nanoparticle probes with high luminescence brightness, narrow emission bandwidth, and long luminescence lifetimes. A Eu complex bearing an amino group was used to react with a functional copolymer poly(styrene-co-maleic anhydride) by the spontaneous amidation reaction, producing the polymer grafted with Eu complexes in the side chains."

Our news journalists obtained a quote from the research from the University of Washington, "The Eu-complex-grafted polymer was further used to prepare Eu-complex-grafted polymer dots (Pdots) and Eu-complex-blended poly(9-vinylcarbazole) composite Pdots, which showed improved colloidal stability as compared to those directly doped with Eu-complex molecules. Both types of Pdots can be efficiently quenched by a nile blue dye, exhibiting much lower detection limit and higher quenching sensitivity as compared to free Eu-complex molecules. Steady-state spectroscopy and time-resolved decay dynamics suggest the quenching mechanism is via efficient fluorescence resonance energy transfer from the Eu complex inside a Pdot to surface dye molecules."

According to the news editors, the research concluded: "The amplified quenching in Eu-complex Pdots, together with efficient cell uptake and specific cell surface labeling observed in mammalian cells, suggests their potential applications in time-resolved bioassays and cellular imaging."

For more information on this research see: Europium-Complex-Grafted Polymer Dots for Amplified Quenching and Cellular Imaging Applications. Langmuir, 2014;30(28):8607-8614. Langmuir can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)

The news correspondents report that additional information may be obtained from Q. Li, University of Washington, Dept. of Chem, Seattle, WA 98195, United States. Additional authors for this research include J.A. Zhang, W. Sun, J.B. Yu, C.F. Wu, W.P. Qin and D.T. Chiu (see also Science).

Keywords for this news article include: Seattle, Science, Washington, United States, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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