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New Findings on Science and Technology from Department of Applied Physics Summarized (Observation of correlated X-ray scattering at atomic resolution)

August 29, 2014

By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Science. According to news reporting originating in Menlo Park, California, by NewsRx journalists, research stated, "Tools to study disordered systems with local structural order, such as proteins in solution, remain limited. Such understanding is essential for e.g. rational drug design."

The news reporters obtained a quote from the research from the Department of Applied Physics, "Correlated X-ray scattering (CXS) has recently attracted new interest as a way to leverage next-generation light sources to study such disordered matter. The CXS experiment measures angular correlations of the intensity caused by the scattering of X-rays from an ensemble of identical particles, with disordered orientation and position. Averaging over 15 496 snapshot images obtained by exposing a sample of silver nanoparticles in solution to a micro-focused synchrotron radiation beam, we report on experimental efforts to obtain CXS signal from an ensemble in three dimensions. A correlation function was measured at wide angles corresponding to atomic resolution that matches theoretical predictions."

According to the news reporters, the research concluded: "These preliminary results suggest that other CXS experiments on disordered ensembles--such as proteins in solution--may be feasible in the future."

For more information on this research see: Observation of correlated X-ray scattering at atomic resolution. Philosophical Transactions, 2014;369(1647):20130315 (see also Science).

Our news correspondents report that additional information may be obtained by contacting D. Mendez, Dept. of Applied Physics, Menlo Park, CA 94025, United States. Additional authors for this research include T.J. Lane, J. Sung, J. Sellberg, C. Levard, H. Watkins, A.E. Cohen, M. Soltis, S. Sutton, J. Spudich, V. Pande, D. Ratner and S. Doniach.

Keywords for this news article include: Science, Menlo Park, California, United States, North and Central America.

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Source: Science Letter

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