Study Findings from Sandia National Laboratories Broaden Understanding of Sensor Research (Label-Free Plasmonic Immunosensing for Plasmodium in a Whole Blood Lysate)
By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Sensor Research have been published. According to news reporting originating in Albuquerque, New Mexico, by NewsRx journalists, research stated, "In this paper, we report an experimental demonstration of malaria pathogen detection in a whole blood lysate using plasmonic nanostructures. The plasmon sensor utilizes extraordinary optical transmission through a nanostructure to directly probe antibody-antigen interactions."
The news reporters obtained a quote from the research from Sandia National Laboratories, "The measured refractive index sensitivity of the nanostructured sensor is 378 nm per refractive index unit in the visible range. The surface chemistry reported here provides highly site directed and stable antibody immobilization. To validate the observed response of the optical sensor, positive and negative control tests were performed. Results confirm that a refractive index change induced by the interaction between immobilized antibodies and malaria parasites is successfully detected by the fabricated sensor."
According to the news reporters, the research concluded: "The demonstrated plasmonic sensor is a compact, highly sensitive, cost effective, selective diagnostic tool for many portable biosensing applications, such as point-of-care diagnostics."
For more information on this research see: Label-Free Plasmonic Immunosensing for Plasmodium in a Whole Blood Lysate. IEEE Sensors Journal, 2014;14(5):1399-1404. IEEE Sensors Journal can be contacted at: Ieee-Inst Electrical Electronics Engineers Inc, 445 Hoes Lane, Piscataway, NJ 08855-4141, USA. (Institute of Electrical and Electronics Engineers - www.ieee.org/; IEEE Sensors Journal - ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=7361)
Our news correspondents report that additional information may be obtained by contacting S.Y. Cho, Sandia Natl Labs, Center Integrated Nanotechnol, Albuquerque, NM 87185, United States. Additional authors for this research include J.L. Briscoe, I.A. Hansen, J.K. Smith, Y.M. Chang and I. Brener (see also Sensor Research).
Keywords for this news article include: New Mexico, Albuquerque, United States, Sensor Research, North and Central America
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