News Column

Studies from Center for Regenerative Medicine Yield New Data on Bioscience (Lung tissue engineering)

August 25, 2014

By a News Reporter-Staff News Editor at Respiratory Therapeutics Week -- Fresh data on Life Science Research are presented in a new report. According to news reporting originating from Boston, Massachusetts, by NewsRx correspondents, research stated, "Lung tissue engineering is an emerging field focused on the development of lung replacement devices and tissue to treat patients with end stage lung disease. Microfluidic based lung assist devices have been developed that have biomimetically designed vascular networks that achieve physiologic blood flow."

Our news editors obtained a quote from the research from Center for Regenerative Medicine, "Gas exchange in these devices occurs across a thin respiratory membrane. Designed for intrathoracic implantation as a bridge to transplant or destination therapy, these lung assist devices will allow ambulation and hospital discharge for patients with end stage lung disease. Decellularized lungs subsequently recellularized with epithelial and endothelial cells have been implanted in small animal models with demonstration of initial gas exchange. Further development of these tissues and scaling to large animal models will validate this approach and may be an organ source for lung transplantation. Initial clinical success has been achieved with decellularized tracheal implants using autologous stem cells."

According to the news editors, the research concluded: "Development of microfluidic lung models using similar architecture to the lung assist device technology allows study of lung biology and diseases with manipulation of lung cells and respiratory membrane strain."

For more information on this research see: Lung tissue engineering. Frontiers In Bioscience, 2014;19():1227-39 (see also Life Science Research).

The news editors report that additional information may be obtained by contacting D.M. Hoganson, Center for Regenerative Medicine, Dept. of Surgery, Massachusetts General Hospital, Boston, MA, United States. Additional authors for this research include E.K. Bassett and J.P Vacanti.

Keywords for this news article include: Boston, Massachusetts, United States, Life Science Research, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Respiratory Therapeutics Week

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