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Findings from Beijing Normal University Provides New Data about DNA Research (Ionic-liquid-assisted desorption of DNA from polyamidoamine-grafted...

August 26, 2014



Findings from Beijing Normal University Provides New Data about DNA Research (Ionic-liquid-assisted desorption of DNA from polyamidoamine-grafted silica nanoparticles surface by a low-salt solution)

By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on DNA Research is now available. According to news originating from Beijing, People's Republic of China, by NewsRx correspondents, research stated, "We studied the influences of imidazolium-based ionic liquids as additives in low ionic strength phosphate solution on releasing DNA from polyamidoamine dendrimer-grafted silica nanoparticle surfaces."

Our news journalists obtained a quote from the research from Beijing Normal University, "The effects of the side-chain length of the imidazolium group, the anion and the concentration of the ionic liquid, the generation of the dendrimer, and the pH and the concentration of the release solution were investigated. It was found that addition of 4 mM 1-hexyl-3-methylimidazolium bromide to 5 mM phosphate at pH 11 could markedly promote the desorption of DNA fragments, with a desorption efficiency of 99.0%."

According to the news editors, the research concluded: "Compared with the conventional strategies employing high-salt solutions or elevated temperature for acceptable recoveries, the method described here enabled quick release of DNA fragments that permitted direct, accurate analysis, and further treatment without desalting."

For more information on this research see: Ionic-liquid-assisted desorption of DNA from polyamidoamine-grafted silica nanoparticles surface by a low-salt solution. Journal of Separation Science, 2014;37(15):2069-2076. Journal of Separation Science can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Journal of Separation Science - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1615-9314)

The news correspondents report that additional information may be obtained from N. Latep, Beijing Normal University, Key Lab Theoret & Computat Photochem, Minist Educ, Coll Chem, Beijing 100875, People's Republic of China. Additional authors for this research include X. Liang and W.D. Qin (see also DNA Research).

Keywords for this news article include: Asia, Beijing, Solvents, DNA Research, Nanoparticle, Ionic Liquids, Nanotechnology, Silicon Nanocrystals, Emerging Technologies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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