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Data on Raman Spectroscopy Detailed by Researchers at Xiamen University [Drop-coating deposition and surface-enhanced Raman spectroscopies (DCDRS and...

August 26, 2014



Data on Raman Spectroscopy Detailed by Researchers at Xiamen University [Drop-coating deposition and surface-enhanced Raman spectroscopies (DCDRS and SERS) provide complementary information of whole human tears]

By a News Reporter-Staff News Editor at Journal of Technology -- Data detailed on Raman Spectroscopy have been presented. According to news reporting originating in Xiamen, People's Republic of China, by VerticalNews journalists, research stated, "Raman spectroscopy has received increasing interest in biomedical applications because of its label-free and in vivo detection capabilities. The main challenge for a wider application lies in its low detection sensitivity, especially for biomolecules."

The news reporters obtained a quote from the research from Xiamen University, "Various strategies have been employed to improve the detection sensitivity of Raman spectroscopy. In this work, we systematically compared two Raman techniques with improved sensitivity for the detection of microliter quantities of whole human tears: drop-coating deposition Raman spectroscopy (DCDRS) and surface-enhanced Raman spectroscopy (SERS). High-quality and highly reproducible DCDR spectra of tears can be obtained in the ring zone of the dried coffee-ring deposit. The major contribution is from the high-abundant proteins, including lysozyme, lactoferrin, and albumin. Good SER spectra with excellent reproducibility can also be acquired in the deposit area and are contributed by uric acid and hypoxanthine in tears with a low abundance but strong interactions with the silver nanoparticles. The result demonstrates that DCDRS is advantageous for detection of some high-abundant components and SERS for some low-abundant components in the whole tears."

According to the news reporters, the research concluded: "A combination of both techniques is able to extract multiparameter information for a systematic analysis of clinical tears and can be further extended to the analysis of other body fluids."

For more information on this research see: Drop-coating deposition and surface-enhanced Raman spectroscopies (DCDRS and SERS) provide complementary information of whole human tears. Journal of Raman Spectroscopy, 2014;45(7):565-573. Journal of Raman Spectroscopy can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Journal of Raman Spectroscopy - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-4555)

Our news correspondents report that additional information may be obtained by contacting P. Hu, Xiamen University, Fujian Prov Key Lab Ophthalmol & Visual Sci, Affiliated Xiamen Eye Center, Eye InstMed College, Xiamen 361005, People's Republic of China. Additional authors for this research include X.S. Zheng, C. Zong, M.H. Li, L.Y. Zhang, W. Li and B. Ren.

Keywords for this news article include: Asia, Xiamen, Raman Spectroscopy, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Journal of Technology


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