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New Findings on Nanoparticles from China University of Science and Technology Summarized (Reversible Fluorescence Switching of Spiropyran-Conjugated...

August 22, 2014



New Findings on Nanoparticles from China University of Science and Technology Summarized (Reversible Fluorescence Switching of Spiropyran-Conjugated Biodegradable Nanoparticles for Super-Resolution Fluorescence Imaging)

By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Nanoparticles. According to news originating from Anhui, People's Republic of China, by NewsRx correspondents, research stated, "We report on the reversible fluorescence switching of biodegradable nanoparticles of spiropyran-terminated poly(epsilon-caprolactone) (SP-PCL) for super-resolution fluorescence imaging. SP-PCL was synthesized via ring-opening polymerization using hydroxyl-containing SP derivative as the initiator."

Our news journalists obtained a quote from the research from the China University of Science and Technology, "SP-PCL solution in THF or dioxane exhibits fast photochromism from colorless to blue upon UV irradiation due to the transformation of SPs in SP-PCL into merocyanines (MCs). Although both SP-PCL solution and MC-PCL solution do not fluoresce, SP-PCL nanoparticle dispersion fabricated via nanoprecipitation in aqueous media, in which SP molecules were embedded into the hydrophobic PCL matrix, displays considerable green emission at 530 nm at an excitation wavelength of 420 nm. Upon

According to the news editors, the research concluded: "Biodegradable SP-PCL nanoparticles are demonstrated to be promising photoswitchable fluorophores for localization-based super-resolution microscopy, evidencing by resolving nanostructures with sub-50 nm resolution in poly(vinyl alcohol) (PVA) film and live cells."

For more information on this research see: Reversible Fluorescence Switching of Spiropyran-Conjugated Biodegradable Nanoparticles for Super-Resolution Fluorescence Imaging. Macromolecules, 2014;47(5):1543-1552. Macromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Macromolecules - www.pubs.acs.org/journal/mamobx)

The news correspondents report that additional information may be obtained from M.Q. Zhu, China University of Science & Technology, Dept. of Polymer Sci & Engn, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, People's Republic of China. Additional authors for this research include G.F. Zhang, Z. Hu, M.P. Aldred, C. Li, W.L. Gong, T. Chen, Z.L. Huang and S.Y. Liu (see also Nanoparticles).

Keywords for this news article include: Asia, Anhui, Nanotechnology, Emerging Technologies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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