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Study Findings from A. Sansone et al Provide New Insights into Experimental Biology (Trpc2 is expressed in two olfactory subsystems, the main and the...

August 19, 2014



Study Findings from A. Sansone et al Provide New Insights into Experimental Biology (Trpc2 is expressed in two olfactory subsystems, the main and the vomeronasal system of larval Xenopus laevis)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Life Science Research have been published. According to news originating from Gottingen, Germany, by NewsRx correspondents, research stated, "Complete segregation of the main olfactory epithelium (MOE) and the vomeronasal epithelium is first observed in amphibians. In contrast, teleost fishes possess a single olfactory surface, in which genetic components of the main and vomeronasal olfactory systems are intermingled."

Our news journalists obtained a quote from the research, "The transient receptor potential channel TRPC2, a marker of vomeronasal neurons, is present in the single fish sensory surface, but is already restricted to the vomeronasal epithelium in a terrestrial amphibian, the red-legged salamander (Plethodon shermani). Here we examined the localization of TRPC2 in an aquatic amphibian and cloned the Xenopus laevis trpc2 gene. We show that it is expressed in both the MOE and the vomeronasal epithelium. This is the first description of a broad trpc2 expression in the MOE of a tetrapod."

According to the news editors, the research concluded: "The expression pattern of trpc2 in the MOE is virtually undistinguishable from that of MOE-specific v2rs, indicating that they are co-expressed in the same neuronal subpopulation."

For more information on this research see: Trpc2 is expressed in two olfactory subsystems, the main and the vomeronasal system of larval Xenopus laevis. Journal of Experimental Biology, 2014;217(13):2235-2238. Journal of Experimental Biology can be contacted at: Company Of Biologists Ltd, Bidder Building Cambridge Commercial Park Cowley Rd, Cambridge CB4 4DL, Cambs, England (see also Life Science Research).

The news correspondents report that additional information may be obtained from A. Sansone, Center Nanoscale Microscopy & Mol Physiol Brain CNMP, D-37073 Gottingen, Germany. Additional authors for this research include A.S. Syed, E. Tantalaki, S.I. Korsching and I. Manzini.

Keywords for this news article include: Europe, Germany, Gottingen, Life Science Research

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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