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Studies from Wake Forest University Yield New Data on Nanotechnology (Hydrodynamic Slip on DNA Observed by Optical Tweezers-Controlled Translocation...

August 19, 2014



Studies from Wake Forest University Yield New Data on Nanotechnology (Hydrodynamic Slip on DNA Observed by Optical Tweezers-Controlled Translocation Experiments with Solid-State and Lipid-Coated Nanopores)

By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Nanotechnology. According to news reporting from Winston Salem, North Carolina, by NewsRx journalists, research stated, "We use optical tweezers to investigate the threading force on a single dsDNA molecule inside silicon-nitride nanopores between 6 and 70 nm in diameter, as well as lipid-coated solid-state nanopores."

The news correspondents obtained a quote from the research from Wake Forest University, "We observe a strong increase of the threading force for decreasing nanopore size that can be attributed to a significant reduction in the electroosmotic flow (EOF), which opposes the electrophoresis. Additionally, we show that the EOF can also be reduced by coating the nanopore wall with an electrically neutral lipid bilayer, resulting in an 85% increase in threading force."

According to the news reporters, the research concluded: "All experimental findings can be described by a quantitative theoretical model that incorporates a hydrodynamic slip effect on the DNA surface with a slip length of 0.5 nm."

For more information on this research see: Hydrodynamic Slip on DNA Observed by Optical Tweezers-Controlled Translocation Experiments with Solid-State and Lipid-Coated Nanopores. Nano Letters, 2014;14(7):4176-4182. Nano Letters can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Nano Letters - www.pubs.acs.org/journal/nalefd)

Our news journalists report that additional information may be obtained by contacting L. Galla, Wake Forest University, Bowman Gray Sch Med, Center Comprehens Canc, Winston Salem, NC 27157, United States. Additional authors for this research include A.J. Meyer, A. Spiering, A. Sischka, M. Mayer, A.R. Hall, P. Reimann and D. Anselmetti (see also Nanotechnology).

Keywords for this news article include: Winston Salem, United States, North Carolina, Nanotechnology, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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