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Studies from University of Michigan in the Area of DNA Research Described (Shell-Engineered Chiroplasmonic Assemblies of Nanoparticles for Zeptomolar...

August 19, 2014



Studies from University of Michigan in the Area of DNA Research Described (Shell-Engineered Chiroplasmonic Assemblies of Nanoparticles for Zeptomolar DNA Detection)

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on DNA Research have been published. According to news reporting out of Ann Arbor, Michigan, by NewsRx editors, research stated, "DNA-bridged pairs of seemingly spherical metallic nanoparticles (NPs) have chiral geometry due to the nonideal oblong shape of the particles and scissor-like conformation."

Our news journalists obtained a quote from the research from the University of Michigan, "Here we demonstrate that deposition of gold and silver shells around the NP heterodimers enables spectral modulation of their chiroplasmonic bands in 400-600 nm region and results in significantly enhanced optical activity with g-factors reaching 1.21 x 10(-2). The multimetal heterodimers optimized for coupling with the spin angular momentum of incident photons enable polymerase chain reaction (PCR)-based DNA detection at the zeptomolar level."

According to the news editors, the research concluded: "This significant improvement in the sensitivity of detection is attributed to improvement of base pairing in the presence of NPs, low background for chiroplasmonic detection protocol, and enhancement of photon-plasmon coupling for light with helicity matching that of the twisted geometry of the heterodimers."

For more information on this research see: Shell-Engineered Chiroplasmonic Assemblies of Nanoparticles for Zeptomolar DNA Detection. Nano Letters, 2014;14(7):3908-3913. Nano Letters can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Nano Letters - www.pubs.acs.org/journal/nalefd)

Our news journalists report that additional information may be obtained by contacting Y. Zhao, University of Michigan, Biointerfaces Inst, Ann Arbor, MI 48109, United States. Additional authors for this research include L.G. Xu, W. Ma, L.B. Wang, H. Kuang, C.L. Xu and N.A. Kotov (see also DNA Research).

Keywords for this news article include: Michigan, Ann Arbor, Engineering, DNA Research, Nanoparticle, United States, Nanotechnology, Emerging Technologies, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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