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RiverVest Venture Partners’ Otonomy Completes $100 Million Initial Public Offering

August 13, 2014

ST. LOUIS & SAN DIEGO--(BUSINESS WIRE)-- Otonomy, a RiverVest Fund II portfolio company that develops drug therapies for the inner and middle ear, announced today its $100 million initial public offering.

The San Diego-based biopharma company priced 6.25 million shares of common stock at a price of $16.00 per share, which starts trading today on the NASDAQ under the symbol OTIC.

Otonomy also granted the underwriters a 30-day option to purchase up to an additional 937,500 shares of common stock which could increase the gross offering to a maximum of $115 million if exercised. Otonomy is expected to have an opening market capitalization of approximately $350 million.

“Otonomy is on the verge of revolutionizing the way doctors treat disorders of the ear,” said John McKearn, Ph.D., RiverVest managing director and Otonomy board member. “This IPO is a significant milestone moving Otonomy forward to help the millions of Americans who suffer from debilitating hearing and balance disorders.”

This IPO represents the latest in a series of successful transactions for RiverVest Venture Fund II that total, including upfront and milestone payments, over $3 billion in transactional value to the investors in these companies.

In addition to Otonomy, RiverVest Fund II’s transactions include:

Company     Location     Sector     Transaction     Acquiror
ZS Pharma     Dallas, TX     Biopharma     IPO in Jun-14     Trades on NASDAQ - ZSPH1
Lumena Pharma.     San Diego, CA     Biopharma     Sold in Jun-14     Shire Plc. (LSE: SHP)
IDEV Technologies     Houston, TX     Med. Device     Sold in Aug-13     Abbott Lab. (NYSE: ABT)
Cameron Health     San Clemente, CA     Med. Device     Sold in Jun-12     Boston Scientific (NYSE: BSX)
Lutonix     Minneapolis, MN     Med. Device     Sold in Dec-11     C.R. Bard (NYSE: BCR)
Excaliard Pharma.     San Diego, CA     Biopharma     Sold in Dec-11     Pfizer Inc. (NYSE: PFE)
Mpex Pharma.     San Diego, CA     Biopharma     Sold in Sep-11     Aptalis Pharma2

1.Subject to 180 day lock-up.

2.Subsequently acquired by Forest Laboratories, Inc. (NYSE: FRX).

About RiverVest Venture Partners®

RiverVest Venture Partners is a venture capital firm focused on identifying and shaping early-stage life science companies to create significant shareholder value. Because of its extensive operating expertise, RiverVest is able to help entrepreneurs achieve near-term objectives that position their companies for exit.

Established in 2000, RiverVest has funded 30 and exited or taken public 18 innovative life science companies and has assets under management of $250 million. For more information, please visit

About Otonomy

Otonomy is developing novel drug therapies for disorders of the inner and middle ear, including: AuriPro, a sustained-release formulation of the antibiotic ciprofloxacin designed to reduce postoperative complications in pediatric patients undergoing tube-placement surgery; OTO-104, a steroid treatment for a rare inner ear disorder called MÉniÈre's disease that disrupts hearing and balance; and, OTO-311, for treating tinnitus, which is slated to enter the clinic next year.

Callaway & Company

Callaway Zuccarello, 314-862-4300

Source: RiverVest Venture Partners

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Source: Business Wire

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