News Column

New Biotechnology Study Results Reported from Technical University (Challenges in industrial fermentation technology research)

August 20, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Technology. According to news reporting originating in Lyngby, Denmark, by NewsRx journalists, research stated, "Industrial fermentation processes are increasingly popular, and are considered an important technological asset for reducing our dependence on chemicals and products produced from fossil fuels. However, despite their increasing popularity, fermentation processes have not yet reached the same maturity as traditional chemical processes, particularly when it comes to using engineering tools such as mathematical models and optimization techniques."

The news reporters obtained a quote from the research from Technical University, "This perspective starts with a brief overview of these engineering tools. However, the main focus is on a description of some of the most important engineering challenges: scaling up and scaling down fermentation processes, the influence of morphology on broth rheology and mass transfer, and establishing novel sensors to measure and control insightful process parameters. The greatest emphasis is on the challenges posed by filamentous fungi, because of their wide applications as cell factories and therefore their relevance in a White Biotechnology context."

According to the news reporters, the research concluded: "Computational fluid dynamics (CFD) is introduced as a promising tool that can be used to support the scaling up and scaling down of bioreactors, and for studying mixing and the potential occurrence of gradients in a tank."

For more information on this research see: Challenges in industrial fermentation technology research. Biotechnology Journal, 2014;9(6):727-38. (Wiley-Blackwell -; Biotechnology Journal -

Our news correspondents report that additional information may be obtained by contacting L.R. Formenti, Dept. of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), Lyngby, Denmark. Additional authors for this research include A. Norregaard, A. Bolic, D.Q. Hernandez, T. Hagemann, A.L. Heins, H. Larsson, L. Mears, M. Mauricio-Iglesias, U. Kruhne and K.V Gernaey (see also Technology).

Keywords for this news article include: Lyngby, Europe, Denmark, Technology, Engineering.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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