The patented technology - called SONS - will be delivered in a simple outpatient procedure that applies small, adjustable and targeted electrical impulses through the nasal cavity to access up to 32 distinct nerve trunks that stimulate the brain. The unique approach has the opportunity to be a low-risk yet highly effective and widely accessible option for addressing various Central Nervous System (CNS) diseases including Alzheimer's.
The SONS technology - or Sphenoid and Olfactory Nerve Stimulation System - may well become a household name someday, thanks to Wedge Therapeutics, which is currently shepherding the technology through the lengthy
"I hear from scores of Alzheimer's families, and it breaks my heart because I am one of them," says Wedge Therapeutics President and CEO,
"SONS can be thought of as a new kind of deep brain stimulation but for the first time it is being done outside the brain - which would be a huge advance," said Dr.
The SONS technology addresses neurological diseases, where treatment has been dominated by pharmaceutical approaches that have invested billions of dollars, but yielded little in terms of meaningful results - perhaps at the expense of simpler, technology-based approaches. Over the past decade, Deep Brain Stimulation (DBS) has been commercialized as an effective treatment option for some neurological diseases, especially Parkinson's. But the implanted devices require complicated and risky brain surgery, costing upwards of
"There are 44 million people in the world estimated to be living with Alzheimer's, and the direct costs of this disease are projected to be more than
Bringing new medical technologies to market is an expensive proposition for any company, and to expedite the regulatory and commercialization of SONS for the vast Alzheimer's community, it is currently looking to raise additional investment and to forge industry partnerships.
SONS may be the "why didn't I think of that?" medical solution of the next decade that Alzheimer's families help shake loose from those who embrace expensive pharma-based and overly complex invasive solutions. And in the process, force conventional wisdom to no longer look down their noses at all the available options. About Wedge Therapeutics Wedge Therapeutics is a privately held medical device development company based in
Keywords for this news article include: Surgery, Technology, Legal Issues,
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