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Investigators at Taishan Medical University Report Findings in Pharmaceutical Research (Optimization of ultrasonic extraction of total flavonoids...

August 22, 2014



Investigators at Taishan Medical University Report Findings in Pharmaceutical Research (Optimization of ultrasonic extraction of total flavonoids from Tussilago farfara L. using response surface methodology)

By a News Reporter-Staff News Editor at Drug Week -- New research on Drugs and Therapies is the subject of a report. According to news reporting originating in Shandong, People's Republic of China, by NewsRx journalists, research stated, "In this work, ultrasound technology was used for the extraction of total flavonoids from Tussilago farfara L. Response surface methodology (RSM), based on a Box-Behnken design (BBD), was used to optimize the effects of processing parameters on total flavonoids yields. The parameters were ultrasonic frequency (X-1), extraction time (X-2) and ratio of liquid to solid (X-3)."

The news reporters obtained a quote from the research from Taishan Medical University, "The statistical analysis indicated that the parameters of ultrasonic power and ratio of liquid to solid, and the square effects among them had significant effects on the yield of flavonoids from Tussilago farfara L. The interaction between ultrasonic power and extraction time, and ultrasonic power and ratio of liquid to solid also caused significant effects on the yields. The optimum extraction conditions were determined as follows: ultrasonic power 420 W, extraction time 30 min, ratio of liquid to solid 25 mL/g."

According to the news reporters, the research concluded: "Under these conditions, the experimental yield 6.59 +/- 0.061% agreed closely with the predicted yield (6.64%)."

For more information on this research see: Optimization of ultrasonic extraction of total flavonoids from Tussilago farfara L. using response surface methodology. Pharmazie, 2014;69(4):311-315. Pharmazie can be contacted at: Govi-Verlag Pharmazeutischer Verlag Gmbh, Pharmazeutisccarl Mannich Str 26, D-65760 Eschborn, Germany. (Wiley-Blackwell - www.wiley.com/; Pharmazie - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1615-1003)

Our news correspondents report that additional information may be obtained by contacting C.H. Liu, Taishan Med Univ, Coll Chem & Chem Engn, Tai An, Shandong, People's Republic of China. Additional authors for this research include K. Qin, Y.X. Qi, K. Li, Y.Q. Li and B.X. Jia (see also Drugs and Therapies).

Keywords for this news article include: Asia, Shandong, Drugs and Therapies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Drug Week


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