Investigators at Seoul National University College of Medicine Zero in on Optical Coherence Tomography (Comparison of ability of time-domain and spectral-domain optical coherence tomography to detect diffuse retinal nerve fiber layer atrophy)
By a News Reporter-Staff News Editor at Health & Medicine Week -- A new study on Optical Coherence Tomography is now available. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, "Our aim was to evaluate and compare diagnostic capabilities of time-domain (Stratus) and spectral-domain (Cirrus) optical coherence tomography (OCT) to detect diffuse retinal nerve fiber layer (RNFL) atrophy. This study assessed 101 eyes from 101 glaucoma patients with diffuse RNFL atrophy and 101 eyes from 101 age-matched healthy individuals."
Our news journalists obtained a quote from the research from the Seoul National University College of Medicine, "Two experienced glaucoma specialists graded red-free RNFL photographs of eyes with diffuse RNFL atrophy using a four-level grading system. The area under the receiver operating characteristic curves (AUC) of normal eyes was compared with that of eyes with diffuse atrophy. Sensitivity and specificity of each OCT device were calculated on the basis of its internal normative database. The largest AUC for Stratus and Cirrus were obtained for average RNFL thicknesses (0.96 and 0.94, respectively). Comparison of the AUC with different RNFL atrophy grades revealed no significant difference between the two OCT devices. Using an internal normative database at a
According to the news editors, the research concluded: "Our results suggest that the diagnostic capabilities of the two instruments to detect diffuse RNFL atrophy are similar."
For more information on this research see: Comparison of ability of time-domain and spectral-domain optical coherence tomography to detect diffuse retinal nerve fiber layer atrophy. Japanese Journal of Ophthalmology, 2013;57(6):529-39. Japanese Journal of Ophthalmology can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer - www.springer.com; Japanese Journal of Ophthalmology - www.springerlink.com/content/0021-5155/)
The news correspondents report that additional information may be obtained from K.E. Kim, Dept. of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea. Additional authors for this research include S.H. Kim, J.W. Jeoung, K.H. Park, T.W. Kim and D.M Kim (see also Optical Coherence Tomography).
The publisher's contact information for the Japanese Journal of Ophthalmology is: Springer, 233 Spring Street, New York, NY 10013, USA.
Keywords for this news article include: Asia, Seoul, South Korea, Imaging Technology, Optical Coherence Tomography.
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