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Findings on Life Science Research Reported by Researchers at Hokkaido University School of Medicine (A proton beam therapy system dedicated to...

August 22, 2014



Findings on Life Science Research Reported by Researchers at Hokkaido University School of Medicine (A proton beam therapy system dedicated to spot-scanning increases accuracy with moving tumors by real-time imaging and gating and reduces ...)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Life Science Research. According to news reporting originating in Hokkaido, Japan, by NewsRx journalists, research stated, "A proton beam therapy (PBT) system has been designed which dedicates to spot-scanning and has a gating function employing the fluoroscopy-based real-time-imaging of internal fiducial markers near tumors. The dose distribution and treatment time of the newly designed real-time-image gated, spot-scanning proton beam therapy (RGPT) were compared with free-breathing spot-scanning proton beam therapy (FBPT) in a simulation."

The news reporters obtained a quote from the research from the Hokkaido University School of Medicine, "In-house simulation tools and treatment planning system VQA (Hitachi, Ltd., Japan) were used for estimating the dose distribution and treatment time. Simulations were performed for 48 motion parameters (including 8 respiratory patterns and 6 initial breathing timings) on CT data from two patients, A and B, with hepatocellular carcinoma and with clinical target volumes 14.6 cc and 63.1 cc. The respiratory patterns were derived from the actual trajectory of internal fiducial markers taken in X-ray real-time tumor-tracking radiotherapy (RTRT). With FBPT, 9/48 motion parameters achieved the criteria of successful delivery for patient A and 0/48 for B. With RGPT 48/48 and 42/48 achieved the criteria. Compared with FBPT, the mean liver dose was smaller with RGPT with statistical significance (p

According to the news reporters, the research concluded: "The proton beam therapy system dedicated to spot-scanning with a gating function for real-time imaging increases accuracy with moving tumors and reduces the physical size, and subsequently the cost of the equipment as well as of the building housing the equipment."

For more information on this research see: A proton beam therapy system dedicated to spot-scanning increases accuracy with moving tumors by real-time imaging and gating and reduces equipment size. Plos One, 2014;9(4):e94971. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

Our news correspondents report that additional information may be obtained by contacting S. Shimizu, Dept. of Radiation Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan. Additional authors for this research include N. Miyamoto, T. Matsuura, Y. Fujii, M. Umezawa, K. Umegaki, K. Hiramoto and H. Shirato (see also Life Science Research).

Keywords for this news article include: Asia, Japan, Therapy, Hokkaido, Life Science Research.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Health & Medicine Week


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