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Findings from National Center for Scientific Research (CNRS) Provide New Insights into Antibiotics (Ion chromatography as highly suitable method for...

August 18, 2014



Findings from National Center for Scientific Research (CNRS) Provide New Insights into Antibiotics (Ion chromatography as highly suitable method for rapid and accurate determination of antibiotic fosfomycin in pharmaceutical wastewater)

By a News Reporter-Staff News Editor at Anti-Infectives Week -- Research findings on Drugs and Therapies are discussed in a new report. According to news reporting originating from Toulouse, France, by NewsRx correspondents, research stated, "A rapid and accurate ion chromatography (IC) method (limit of detection as low as 0.06 mg L-1) for fosfomycin concentration determination in pharmaceutical industrial wastewater was developed. This method was compared with the performance of high performance liquid chromatography determination (with a high detection limit of 96.0 mg L-1) and ultraviolet spectrometry after reacting with alizarin (difficult to perform in colored solutions)."

Our news editors obtained a quote from the research from National Center for Scientific Research (CNRS), "The accuracy of the IC method was established in the linear range of 1.0-15.0 mg L-1 and a linear correlation was found with a correlation coefficient of 0.9998. The recoveries of fosfomycin from industrial pharmaceutical wastewater at spiking concentrations of 2.0, 5.0 and 8.0 mg L-1 ranged from 81.91 to 94.74%, with a relative standard deviation (RSD) from 1 to 4%. The recoveries of effluent from a sequencing batch reactor treated fosfomycin with activated sludge at spiking concentrations of 5.0, 8.0, 10.0 mg L-1 ranging from 98.25 to 99.91%, with a RSD from 1 to 2%."

According to the news editors, the research concluded: "The developed IC procedure provided a rapid, reliable and sensitive method for the determination of fosfomycin concentration in industrial pharmaceutical wastewater and samples containing complex components."

For more information on this research see: Ion chromatography as highly suitable method for rapid and accurate determination of antibiotic fosfomycin in pharmaceutical wastewater. Water Science and Technology, 2014;69(10):2014-2022. Water Science and Technology can be contacted at: Iwa Publishing, Alliance House, 12 Caxton St, London SW1H0QS, England. (IWA Publishing - www.iwaponline.com; Water Science and Technology - www.iwaponline.com/wst)

The news editors report that additional information may be obtained by contacting P. Zeng, UMR 792 INSA INRA, UMR INSA CNRS 5504, Lab Ingn Syst Biol & Proc, F-31077 Toulouse 4, France. Additional authors for this research include X.L. Xie, Y.H. Song, R.X. Liu, C.W. Zhu, A. Galarneau and J.S. Pic (see also Drugs and Therapies).

Keywords for this news article include: Antibacterial, Antibiotics, Antimicrobials, France, Europe, Toulouse, Fosfomycin, Phosphonic Acids, Drugs and Therapies, Urinary Antiinfectives

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Anti-Infectives Week


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