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University of Malaysia Details Findings in DNA Research (Application of Gold Nanoparticles for Electrochemical DNA Biosensor)

July 16, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on DNA Research have been published. According to news reporting out of Kangar, Malaysia, by NewsRx editors, research stated, "An electrochemical DNA biosensor was successfully fabricated by using (3-aminopropyl)triethoxysilane (APTES) as a linker molecule combined with the gold nanoparticles (GNPs) on thermally oxidized SiO2 thin films. The SiO2 thin films surface was chemically modified with a mixture of APTES and GNPs for DNA detection in different time periods of 30 min, 1 hour, 2 hours, and 4 hours, respectively."

Our news journalists obtained a quote from the research from the University of Malaysia, "The DNA immobilization and hybridization were conducted by measuring the differences of the capacitance value within the frequency range of 1Hz to 1MHz. The capacitance values for DNA immobilization were 160 mu F, 77.8 mu F, 70 mu F, and 64.6 mu F, respectively, with the period of time from 30 min to 4 hours. Meanwhile the capacitance values for DNA hybridization were 44 mu F, 54 mu F, 55 mu F, and 61.5 mu F, respectively. The capacitance value of bare SiO2 thin film was 0.42 mu F, which was set as a base line for a reference in DNA detection."

According to the news editors, the research concluded: "The differences of the capacitance value between the DNA immobilization and hybridization revealed that the modified SiO2 thin films using APTES and GNPs were successfully developed for DNA detection."

For more information on this research see: Application of Gold Nanoparticles for Electrochemical DNA Biosensor. Journal of Nanomaterials, 2014;():1-7. Journal of Nanomaterials can be contacted at: Hindawi Publishing Corporation, 410 Park Avenue, 15TH Floor, #287 Pmb, New York, NY 10022, USA. (Hindawi Publishing -; Journal of Nanomaterials -

Our news journalists report that additional information may be obtained by contacting A.M. Mohammed, Univ Malaysia Perlis, Inst Nano Elect Engn, Kangar 01000, Perlis, Malaysia. Additional authors for this research include R.A. Rahim, I.J. Ibraheem, F.K. Loong, H. Hisham, U. Hashim and Y. Al-Douri (see also DNA Research).

Keywords for this news article include: Asia, Kangar, Malaysia, Chemistry, Biosensing, DNA Research, Nanoparticle, Bioengineering, Electrochemical, Bionanotechnology, Nanobiotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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