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Study Data from M.D. Anderson Cancer Center Update Knowledge of Biotechnology (Technologies for deriving primary tumor cells for use in personalized...

July 15, 2014



Study Data from M.D. Anderson Cancer Center Update Knowledge of Biotechnology (Technologies for deriving primary tumor cells for use in personalized cancer therapy)

By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators discuss new findings in Technology. According to news reporting originating in Houston, Texas, by NewsRx journalists, research stated, "For decades, immortal cancer cell lines have constituted an accessible, easily usable set of biological models to investigate cancer biology and explore the potential efficacy of anticancer drugs. However, numerous studies have suggested that these cell lines poorly represent the diversity, heterogeneity, and drug-resistant tumors occurring in patients."

The news reporters obtained a quote from the research from M.D. Anderson Cancer Center, "The derivation and short-term culture of primary cells from solid tumors have thus gained significant importance in personalized cancer therapy. This review focuses on our current understanding and the pros and cons of different methods for primary tumor cell culture. Furthermore, various culture matrices such as biomimetic scaffolds and chemically defined media supplemented with essential nutrients, have been prepared for different tissues."

According to the news reporters, the research concluded: "These well-characterized primary tumor cells redefine cancer therapies with high translational relevance."

For more information on this research see: Technologies for deriving primary tumor cells for use in personalized cancer therapy. Trends In Biotechnology, 2013;31(6):347-54. (Elsevier - www.elsevier.com; Trends In Biotechnology - www.elsevier.com/wps/product/cws_home/405917)

Our news correspondents report that additional information may be obtained by contacting A. Mitra, Dept. of Pediatrics, Unit 853, The University of Texas MD Anderson Cancer Center, 1515 Holocombe Blvd, Houston, Texas 77030, United States. Additional authors for this research include L. Mishra and S. Li (see also Technology).

Keywords for this news article include: Texas, Cancer, Houston, Therapy, Oncology, Technology, United States, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Weekly


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